Use of rituximab in lymphomatoid granulomatosis with isolated central nervous system involvement.

haematology (drugs and medicines) malignant and benign haematology malignant disease and immunosuppression neurooncology neurosurgery

Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
07 Sep 2020
Historique:
entrez: 9 9 2020
pubmed: 10 9 2020
medline: 12 3 2021
Statut: epublish

Résumé

A 33-year-old woman presented to the emergency room with severe headaches. A CT scan of the head revealed two brain lesions with associated vasogenic oedema. Diagnostic resection of one of the lesions followed by pathological analysis revealed grade III lymphomatoid granulomatosis (LYG). Staging investigations elsewhere in the body were negative, isolating this case of LYG to the central nervous system, an atypical presentation. After the resection, she was treated with single-agent rituximab 375 mg/m

Identifiants

pubmed: 32900727
pii: 13/9/e235412
doi: 10.1136/bcr-2020-235412
pmc: PMC7478030
pii:
doi:

Substances chimiques

Antineoplastic Agents, Immunological 0
Rituximab 4F4X42SYQ6

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Jesse Mooneyham (J)

Texas A&M Health Science Center College of Medicine, Houston, Texas, USA.

Cesar Gentille (C)

Houston Methodist Cancer Center, Houston, Texas, USA cgentillesanchez@houstonmethodist.org.

Andrea Barbieri (A)

Department of Hematopathology, Houston Methodist Hospital, Houston, Texas, USA.

Shilpan Shah (S)

Houston Methodist Cancer Center, Houston, Texas, USA.

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Classifications MeSH