Emergency Embolization of Pelvic Vessels in Patients With Locally Advanced Cervical Cancer and Massive Vaginal Bleeding: A Case Series in a Latin American Oncological Center.
Journal
JCO global oncology
ISSN: 2687-8941
Titre abrégé: JCO Glob Oncol
Pays: United States
ID NLM: 101760170
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
entrez:
9
9
2020
pubmed:
10
9
2020
medline:
29
7
2021
Statut:
ppublish
Résumé
Locally advanced cervical cancer may present with uncontrollable vaginal bleeding in up to 70% of cases. Pelvic vessel embolization has been used as an urgent maneuver for achieving fast hemostatic control. This report describes outcomes of selective pelvic vessel embolization in patients with severe bleeding due to a locally advanced cervical cancer. In this retrospective study, technical aspects, clinical variables, and bleeding-related morbidity were described. The frequency of recurrent disease and the vital status at 1 year of follow-up were determined. Analysis was performed with statistical software R, version 3.6.2. The setting was Instituto Nacional de Cancerología- Bogotá, Colombia, between January 2009 and July 2017. A total of 47 patients were included. Median age was 44 years (range, 26-70 years). The pre-embolization median hemoglobin level was 7.9 g/dL (range, 5.0-11.3 g/dL). Blood transfusions were administered to 41 women (87.2%). Bleeding control was achieved in 95.7% of cases in the first 24 hours after the embolization. There were no major complications. In 17 cases (36.2%), minor complications were reported; the most common was pelvic pain. In 17.1% of cases, a second embolization was required. After 12 months of follow-up, 27.7% of patients were alive without disease, 44.7% were alive with disease, and 25.5% of them have died of cervical cancer progression. Selective pelvic vessel embolization is a useful alternative in patients with locally advanced cervical cancer and life-threatening bleeding. Its impact on recurrent disease and death due to oncologic cause is not clear.
Identifiants
pubmed: 32903119
doi: 10.1200/GO.20.00239
pmc: PMC7529508
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1376-1383Références
Semin Intervent Radiol. 2008 Dec;25(4):378-86
pubmed: 21326579
Br J Radiol. 1994 Jun;67(798):530-4
pubmed: 8032805
AJR Am J Roentgenol. 1976 May;126(5):1028-32
pubmed: 178224
Radiographics. 2012 Oct;32(6):1713-31
pubmed: 23065166
J Vasc Interv Radiol. 2003 Sep;14(9 Pt 2):S199-202
pubmed: 14514818
J Cancer Res Ther. 2013 Oct-Dec;9(4):672-9
pubmed: 24518716
Semin Intervent Radiol. 2006 Sep;23(3):240-8
pubmed: 21326770
Cancer Epidemiol. 2016 Sep;44 Suppl 1:S121-S130
pubmed: 27678314
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Eur J Gynaecol Oncol. 2016;37(5):736-740
pubmed: 29787023
Radiology. 1973 Oct;109(1):65-70
pubmed: 4783129
Taiwan J Obstet Gynecol. 2016 Aug;55(4):607-8
pubmed: 27590393
Cochrane Database Syst Rev. 2019 Mar 19;3:CD011000
pubmed: 30888060
Ginecol Obstet Mex. 2015 May;83(5):289-93
pubmed: 26233974
Clin Transl Imaging. 2017;5(4):373-388
pubmed: 28804704
Maedica (Bucur). 2011 Apr;6(2):137-40
pubmed: 22205897
Int J Radiat Oncol Biol Phys. 2005 Aug 1;62(5):1399-404
pubmed: 16029799
Acta Radiol. 2018 Nov;59(11):1336-1342
pubmed: 29448806
Lancet Oncol. 2015 Oct;16(14):1405-38
pubmed: 26522157
Radiology. 1989 Aug;172(2):337-9
pubmed: 2748811
Eurasian J Med. 2010 Dec;42(3):153-6
pubmed: 25610148
Cancer Invest. 2002;20(5-6):754-8
pubmed: 12197232