Outcomes following use of a standard antibiotic protocol in the management of maxillofacial trauma patients.
Antibiotics
Facial fractures
Infection
Protocol
Surgical site
Journal
Journal of oral biology and craniofacial research
ISSN: 2212-4268
Titre abrégé: J Oral Biol Craniofac Res
Pays: Netherlands
ID NLM: 101619156
Informations de publication
Date de publication:
Historique:
received:
24
04
2020
revised:
08
08
2020
accepted:
09
08
2020
entrez:
9
9
2020
pubmed:
10
9
2020
medline:
10
9
2020
Statut:
ppublish
Résumé
To evaluate the effectiveness of a standard antibiotic regimen protocol in the management of maxillofacial trauma patients. The study sample included patients with at least one facial fracture and managed by either closed (CR/MMF) or open reduction (ORIF) by the Oral and Maxillofacial Surgery service. A standardized antibiotic administration protocol based on type of treatment performed and timing of surgical intervention was used in the management of all patients. The primary predictor variable was antibiotic usage. The primary outcome measured was postoperative surgical site infection. Bivariate analysis was performed to assess the association between antibiotic exposure and postoperative surgical site infection. A p value of less than or equal to .05 was deemed to be significant. The study sample comprised of 392 patients (102 midface and 290 mandible fractures). The mean age of the study group was 35 years and 89% of the patients were male. Postoperative infection was encountered in 18 patients (all with compound mandible fractures). The infection rates were 3.6% after CR/MMF and 8.7% after ORIF. No patient with midface fractures developed an infection. Chi-square test showed no statistically significant difference in postoperative infection rate in mandible fractures treated either by CR/MMF (p = 0.91) or ORIF (p = 0.94). Use of this antibiotic administration protocol limits antibiotic usage and standardizes their administration in the management of maxillofacial trauma without increasing the rate of postoperative surgical site infections.
Identifiants
pubmed: 32904248
doi: 10.1016/j.jobcr.2020.08.009
pii: S2212-4268(20)30125-1
pmc: PMC7452338
doi:
Types de publication
Journal Article
Langues
eng
Pagination
519-522Informations de copyright
© 2020 Craniofacial Research Foundation. Published by Elsevier B.V. All rights reserved.
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