Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread.


Journal

Journal of surgical case reports
ISSN: 2042-8812
Titre abrégé: J Surg Case Rep
Pays: England
ID NLM: 101560169

Informations de publication

Date de publication:
Aug 2020
Historique:
received: 13 05 2020
accepted: 29 06 2020
entrez: 9 9 2020
pubmed: 10 9 2020
medline: 10 9 2020
Statut: epublish

Résumé

Metastatic breast carcinoma is a relatively common clinical entity. However, the prognosis of oligometastatic and polygometastatic disease differs considerably pertaining to five-year survival. Metastatic breast carcinoma to the sternum has been described as early as 1988. We describe two cases in our institution who presented with solitary sternal metastases with a previous history of treated breast cancer. In both cases, there had been a history of previous left breast cancer treated aggressively with surgical resection and adjuvant oncological therapy and maintenance hormonal therapy. Partial sternectomy or total sternectomy for solitary metastatic sternal deposits is well established with relatively low morbidity and mortality and improvement in quality of life and possible improvement in long-term survival. Furthermore, reconstructive options are inherently dependent on extent of resection performed. These techniques can incorporate the use of sternal plates in order to approximate defects and reinforce the sternum in the setting of partial sternectomy.

Identifiants

pubmed: 32904681
doi: 10.1093/jscr/rjaa272
pii: rjaa272
pmc: PMC7458144
doi:

Types de publication

Case Reports

Langues

eng

Pagination

rjaa272

Informations de copyright

Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.

Références

Rom J Morphol Embryol. 2018;59(4):1225-1232
pubmed: 30845305
J Vis Surg. 2017 Jul 26;3:95
pubmed: 29078657
J Thorac Dis. 2017 Nov;9(11):4336-4346
pubmed: 29268502
Innovations (Phila). 2018 Jul/Aug;13(4):309-311
pubmed: 29994933
Cancer. 1988 Oct 1;62(7):1397-401
pubmed: 3416279
J Thorac Cardiovasc Surg. 1997 Jul;114(1):93-9
pubmed: 9240298
Cochrane Database Syst Rev. 2018 Mar 15;3:CD011276
pubmed: 29542106
Ann Surg Oncol. 2008 May;15(5):1322-9
pubmed: 18239972
J Vasc Interv Radiol. 2014 Nov;25(11):1665-70
pubmed: 25255705
J Thorac Cardiovasc Surg. 1965 Mar;49:357-63
pubmed: 14265951

Auteurs

Saifullah Mohamed (S)

Department of Cardiothoracic Surgery, Royal Stoke University Hospital, Stoke On Trent, UK.

Khurum Mazhar (K)

Department of Cardiothoracic Surgery, Royal Stoke University Hospital, Stoke On Trent, UK.

Ahmed Osman (A)

Department of Cardiothoracic Surgery, Royal Stoke University Hospital, Stoke On Trent, UK.

Akshay Patel (A)

Department of Cardiothoracic Surgery, Royal Stoke University Hospital, Stoke On Trent, UK.

Lakshmi Srinivasan (L)

Department of Cardiothoracic Surgery, Royal Stoke University Hospital, Stoke On Trent, UK.

Shilajit Ghosh (S)

Department of Cardiothoracic Surgery, Royal Stoke University Hospital, Stoke On Trent, UK.

Classifications MeSH