Preparation and Characterization of Electrospun Collagen Based Composites for Biomedical Applications.

Dynamic Vapor Sorption (DVS) FTIR-ATR spectroscopy PET cell growth collagen nanofibrous mats

Journal

Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929

Informations de publication

Date de publication:
07 Sep 2020
Historique:
received: 07 08 2020
revised: 01 09 2020
accepted: 04 09 2020
entrez: 10 9 2020
pubmed: 11 9 2020
medline: 11 9 2020
Statut: epublish

Résumé

Electrospinning is a widely used technology for obtaining nanofibers from synthetic and natural polymers. In this study, electrospun mats from collagen (C), polyethylene terephthalate (PET) and a blend of the two (C-PET) were prepared and stabilized through a cross-linking process. The aim of this research was to prepare and characterize the nanofiber structure by Fourier-transform infrared with attenuated total reflectance spectroscopy (FTIR-ATR) in close correlation with dynamic vapor sorption (DVS). The studies indicated that C-PET nanofibrous mats shows improved mechanical properties compared to collagen samples. A correlation between morphological, structural and cytotoxic proprieties of the studied samples were emphasized and the results suggest that the prepared nanofiber mats could be a promising candidate for tissue-engineering applications, especially dermal applications.

Identifiants

pubmed: 32906790
pii: ma13183961
doi: 10.3390/ma13183961
pmc: PMC7559754
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : European Regional Development Fund
ID : 86/2016

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Auteurs

Mioara Drobota (M)

Physics of Polymers and Polymeric Materials, "Petru Poni" Institute of Macromolecular Chemistry, Aleea Grigore Ghica Voda, 41A, 700487 Iasi, Romania.

Luiza Madalina Gradinaru (LM)

Physics of Polymers and Polymeric Materials, "Petru Poni" Institute of Macromolecular Chemistry, Aleea Grigore Ghica Voda, 41A, 700487 Iasi, Romania.

Stelian Vlad (S)

Physics of Polymers and Polymeric Materials, "Petru Poni" Institute of Macromolecular Chemistry, Aleea Grigore Ghica Voda, 41A, 700487 Iasi, Romania.

Alexandra Bargan (A)

Physics of Polymers and Polymeric Materials, "Petru Poni" Institute of Macromolecular Chemistry, Aleea Grigore Ghica Voda, 41A, 700487 Iasi, Romania.

Maria Butnaru (M)

Physics of Polymers and Polymeric Materials, "Petru Poni" Institute of Macromolecular Chemistry, Aleea Grigore Ghica Voda, 41A, 700487 Iasi, Romania.
Department of Biomedical Sciences, "Grigore T. Popa" University of Medicine and Pharmacy, 9-13, Kogalniceanu Street, 700115 Iași, Romania.

Marian Angheloiu (M)

Sanimed International IMPEX SRL, Sos. București Măgurele 70F, 051434 Bucharest, Romania.

Magdalena Aflori (M)

Physics of Polymers and Polymeric Materials, "Petru Poni" Institute of Macromolecular Chemistry, Aleea Grigore Ghica Voda, 41A, 700487 Iasi, Romania.

Classifications MeSH