The Precision Oncology Program for Cancer of the Prostate (POPCaP) Network: A Veterans Affairs/Prostate Cancer Foundation Collaboration.


Journal

Federal practitioner : for the health care professionals of the VA, DoD, and PHS
ISSN: 1078-4497
Titre abrégé: Fed Pract
Pays: United States
ID NLM: 9500574

Informations de publication

Date de publication:
Aug 2020
Historique:
entrez: 10 9 2020
pubmed: 11 9 2020
medline: 11 9 2020
Statut: ppublish

Résumé

The promise of precision oncology only can be realized when genetic alterations are identified that can be lever-aged to improve response and minimize toxicity. Identifying those alterations as efficiently as possible and then giving patients access to targeted therapy and clinical study requires a comprehensive strategy across health care systems. The US Department of Veterans Affairs (VA) and Prostate Cancer Foundation have established a network of VA centers to help develop best practices for precision oncology for the treatment of veterans with advanced prostate cancer. This article describes the genesis and structure of this network and its potential for contributing to care and research in the VA and the health care system as a whole. The Precision Oncology Program for Cancer of the Prostate network and its partnership with VA clinical and research efforts is anticipated to provide important insights into barriers and solutions to the implementation of precision oncology for prostate cancer across the VA.

Sections du résumé

BACKGROUND BACKGROUND
The promise of precision oncology only can be realized when genetic alterations are identified that can be lever-aged to improve response and minimize toxicity. Identifying those alterations as efficiently as possible and then giving patients access to targeted therapy and clinical study requires a comprehensive strategy across health care systems.
OBSERVATIONS METHODS
The US Department of Veterans Affairs (VA) and Prostate Cancer Foundation have established a network of VA centers to help develop best practices for precision oncology for the treatment of veterans with advanced prostate cancer. This article describes the genesis and structure of this network and its potential for contributing to care and research in the VA and the health care system as a whole.
CONCLUSIONS CONCLUSIONS
The Precision Oncology Program for Cancer of the Prostate network and its partnership with VA clinical and research efforts is anticipated to provide important insights into barriers and solutions to the implementation of precision oncology for prostate cancer across the VA.

Identifiants

pubmed: 32908353
doi: 10.12788/fp.0021
pii: fp-37-7s-s48
pmc: PMC7473728
doi:

Types de publication

Journal Article

Langues

eng

Pagination

S48-S53

Informations de copyright

Copyright © 2020 Frontline Medical Communications Inc., Parsippany, NJ, USA.

Déclaration de conflit d'intérêts

Author Disclosures The authors reports no actual or potential conflicts of interest with regard to this article.

Références

Am Soc Clin Oncol Educ Book. 2018 May 23;38:726-739
pubmed: 30231382
Cell. 2018 Jul 26;174(3):758-769.e9
pubmed: 30033370
Nature. 2005 Apr 14;434(7035):917-21
pubmed: 15829967
N Engl J Med. 1998 Sep 24;339(13):924-5
pubmed: 9750095
Cancer Epidemiol Biomarkers Prev. 2014 Mar;23(3):437-49
pubmed: 24425144
JAMA Oncol. 2019 Apr 1;5(4):471-478
pubmed: 30589920
N Engl J Med. 2020 May 28;382(22):2091-2102
pubmed: 32343890
Cell. 2015 May 21;161(5):1215-1228
pubmed: 26000489
PLoS One. 2020 May 26;15(5):e0233260
pubmed: 32453797
N Engl J Med. 2016 Aug 4;375(5):443-53
pubmed: 27433846
N Engl J Med. 2016 Nov 3;375(18):1804-5
pubmed: 27806229

Auteurs

Bruce Montgomery (B)

is an Oncologist and is Network Director at VA Puget Sound Health Care System in Seattle, Washington. is an Oncologist at the Greater Los Angeles Health Care System and a Professor of Medicine at the University of California, Los Angeles. is Program Director, Million Veteran Program. is Scientific Program Manager of Oncology and is Chief Research and Development Officer, all in the Office of Research and Development, Veterans Health Administration. Bruce Montgomery is a Professor of Medicine at the University of Washington in Seattle.

Matthew Rettig (M)

is an Oncologist and is Network Director at VA Puget Sound Health Care System in Seattle, Washington. is an Oncologist at the Greater Los Angeles Health Care System and a Professor of Medicine at the University of California, Los Angeles. is Program Director, Million Veteran Program. is Scientific Program Manager of Oncology and is Chief Research and Development Officer, all in the Office of Research and Development, Veterans Health Administration. Bruce Montgomery is a Professor of Medicine at the University of Washington in Seattle.

Jesse Kasten (J)

is an Oncologist and is Network Director at VA Puget Sound Health Care System in Seattle, Washington. is an Oncologist at the Greater Los Angeles Health Care System and a Professor of Medicine at the University of California, Los Angeles. is Program Director, Million Veteran Program. is Scientific Program Manager of Oncology and is Chief Research and Development Officer, all in the Office of Research and Development, Veterans Health Administration. Bruce Montgomery is a Professor of Medicine at the University of Washington in Seattle.

Sumitra Muralidhar (S)

is an Oncologist and is Network Director at VA Puget Sound Health Care System in Seattle, Washington. is an Oncologist at the Greater Los Angeles Health Care System and a Professor of Medicine at the University of California, Los Angeles. is Program Director, Million Veteran Program. is Scientific Program Manager of Oncology and is Chief Research and Development Officer, all in the Office of Research and Development, Veterans Health Administration. Bruce Montgomery is a Professor of Medicine at the University of Washington in Seattle.

Kenute Myrie (K)

is an Oncologist and is Network Director at VA Puget Sound Health Care System in Seattle, Washington. is an Oncologist at the Greater Los Angeles Health Care System and a Professor of Medicine at the University of California, Los Angeles. is Program Director, Million Veteran Program. is Scientific Program Manager of Oncology and is Chief Research and Development Officer, all in the Office of Research and Development, Veterans Health Administration. Bruce Montgomery is a Professor of Medicine at the University of Washington in Seattle.

Rachel Ramoni (R)

is an Oncologist and is Network Director at VA Puget Sound Health Care System in Seattle, Washington. is an Oncologist at the Greater Los Angeles Health Care System and a Professor of Medicine at the University of California, Los Angeles. is Program Director, Million Veteran Program. is Scientific Program Manager of Oncology and is Chief Research and Development Officer, all in the Office of Research and Development, Veterans Health Administration. Bruce Montgomery is a Professor of Medicine at the University of Washington in Seattle.

Classifications MeSH