Investigation Report of cVDPV2 Outbreak in Bokh Woreda of Dollo Zone, Somali Regional State, Ethiopia.


Journal

Case reports in infectious diseases
ISSN: 2090-6625
Titre abrégé: Case Rep Infect Dis
Pays: Egypt
ID NLM: 101573243

Informations de publication

Date de publication:
2020
Historique:
received: 29 02 2020
revised: 27 07 2020
accepted: 20 08 2020
entrez: 10 9 2020
pubmed: 11 9 2020
medline: 11 9 2020
Statut: epublish

Résumé

Poliovirus isolates detected in persons or in the environment can fall into three major categories: wild, Sabin and Sabin-like, or vaccine-derived. Detection of wild or vaccine-derived poliovirus may constitute an emergency, which can be categorized as an event that can lead to an outbreak, depending on characteristics of the isolate and the context in which it appears. The aim of the study was investigation report of cVDPV2 outbreak in Bokh woreda of Dollo Zone, Somali regional state, Ethiopia. A team of experts drawn from different organizations was deployed to Bokh woreda to make detailed field investigation from May 25 to June 17, 2019. By using standard World Health Organization polio outbreak investigation checklist, document review of surveillance, immunization, and clinical data related to the case was made. Key informant's interview was made to health professionals, managers, parents of case, woreda and kebele leaders, religious leaders, and HEWs related to acute flaccid paralysis outbreak. The notified AFP case was a 39-month-old female from Angalo kebele of Bokh woreda, Dollo Zone. On 19th May 2019, the patient developed high grade fever and was taken to Angalo Health Post on 20th May 2019. As per the examination by a health extension worker, the child had high grade fever and neck stiffness with preliminary diagnosis of meningitis for which ceftriaxone injection was prescribed. Contact sample was taken from three children on 28th May 2019 and 29th May 2019 and was sent to Addis Ababa National Polio Laboratory. All contact stool samples were found to be positive for poliovirus type 2 and referred for sequencing in National Institute of Communicable Diseases (NICD), South Africa, the Regional Polio Reference Laboratory.

Sections du résumé

BACKGROUND BACKGROUND
Poliovirus isolates detected in persons or in the environment can fall into three major categories: wild, Sabin and Sabin-like, or vaccine-derived. Detection of wild or vaccine-derived poliovirus may constitute an emergency, which can be categorized as an event that can lead to an outbreak, depending on characteristics of the isolate and the context in which it appears. The aim of the study was investigation report of cVDPV2 outbreak in Bokh woreda of Dollo Zone, Somali regional state, Ethiopia.
METHODS METHODS
A team of experts drawn from different organizations was deployed to Bokh woreda to make detailed field investigation from May 25 to June 17, 2019. By using standard World Health Organization polio outbreak investigation checklist, document review of surveillance, immunization, and clinical data related to the case was made. Key informant's interview was made to health professionals, managers, parents of case, woreda and kebele leaders, religious leaders, and HEWs related to acute flaccid paralysis outbreak.
RESULT RESULTS
The notified AFP case was a 39-month-old female from Angalo kebele of Bokh woreda, Dollo Zone. On 19th May 2019, the patient developed high grade fever and was taken to Angalo Health Post on 20th May 2019. As per the examination by a health extension worker, the child had high grade fever and neck stiffness with preliminary diagnosis of meningitis for which ceftriaxone injection was prescribed. Contact sample was taken from three children on 28th May 2019 and 29th May 2019 and was sent to Addis Ababa National Polio Laboratory. All contact stool samples were found to be positive for poliovirus type 2 and referred for sequencing in National Institute of Communicable Diseases (NICD), South Africa, the Regional Polio Reference Laboratory.

Identifiants

pubmed: 32908734
doi: 10.1155/2020/6917313
pmc: PMC7471813
doi:

Types de publication

Case Reports

Langues

eng

Pagination

6917313

Informations de copyright

Copyright © 2020 Diriba Sufa and Urge Gerema.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest.

Références

MMWR Morb Mortal Wkly Rep. 2019 Mar 08;68(9):225-230
pubmed: 30845121
East Afr Med J. 2008 May;85(5):222-31
pubmed: 18814532
BMC Infect Dis. 2018 Jan 5;18(1):9
pubmed: 29304745
MMWR Morb Mortal Wkly Rep. 2018 Mar 16;67(10):300-305
pubmed: 29543791
PLoS Med. 2013;10(3):e1001405
pubmed: 23526886
BMC Infect Dis. 2015 Feb 18;15:66
pubmed: 25886823
J Korean Med Sci. 2007 Apr;22(2):362-4
pubmed: 17449951
MMWR Morb Mortal Wkly Rep. 2018 Jun 22;67(24):690-694
pubmed: 29927908
BMC Infect Dis. 2016 Jun 10;16:277
pubmed: 27287521
MMWR Morb Mortal Wkly Rep. 2019 Nov 15;68(45):1024-1028
pubmed: 31725706
N Engl J Med. 2018 Aug 30;379(9):834-845
pubmed: 30157398
Health Aff (Millwood). 2016 Feb;35(2):277-83
pubmed: 26858381
BMC Infect Dis. 2018 Apr 13;18(1):176
pubmed: 29653509

Auteurs

Diriba Sufa (D)

Ethiopian Public Health Institute (EPHI), Center for Public Health Emergency Management (cPHEM), Addis Ababa, Ethiopia.

Urge Gerema (U)

Department of Biomedical Sciences, Division of Anatomy, College of Medical Sciences, Institute of Health Sciences, Jimma University, Jimma, Ethiopia.

Classifications MeSH