Diffuse Spontaneous Laryngeal Hemorrhage with Trastuzumab.
Journal
Case reports in otolaryngology
ISSN: 2090-6765
Titre abrégé: Case Rep Otolaryngol
Pays: United States
ID NLM: 101576603
Informations de publication
Date de publication:
2020
2020
Historique:
received:
21
05
2020
accepted:
12
08
2020
entrez:
10
9
2020
pubmed:
11
9
2020
medline:
11
9
2020
Statut:
epublish
Résumé
Drug-induced epithelial hemorrhage of the endolarynx is an unusual etiology of hemoptysis. We present a case of hemoptysis in a young female patient undergoing treatment for metastatic breast cancer with trastuzumab emtansine. Though previously associated with diffuse spontaneous hemorrhage of the gingiva, there have not been reports of laryngeal hemorrhage with trastuzumab emtansine treatment. In this case report, we suggest that trastuzumab emtansine played a contributory role in the development of diffuse epithelial laryngeal hemorrhage and describe the pathophysiology, history, laryngoscopic findings, and management of this condition.
Identifiants
pubmed: 32908757
doi: 10.1155/2020/8818905
pmc: PMC7463383
doi:
Types de publication
Case Reports
Langues
eng
Pagination
8818905Informations de copyright
Copyright © 2020 Lauren Klute et al.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest regarding the publication of this article.
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