County-level exposures to greenness and associations with COVID-19 incidence and mortality in the United States.

Coronavirus environmental health epidemiology green space

Journal

medRxiv : the preprint server for health sciences
Titre abrégé: medRxiv
Pays: United States
ID NLM: 101767986

Informations de publication

Date de publication:
16 Nov 2020
Historique:
pubmed: 11 9 2020
medline: 11 9 2020
entrez: 10 9 2020
Statut: epublish

Résumé

COVID-19 is an infectious disease that has killed more than 246,000 people in the US. During a time of social distancing measures and increasing social isolation, green spaces may be a crucial factor to maintain a physically and socially active lifestyle while not increasing risk of infection. We evaluated whether greenness is related to COVID-19 incidence and mortality in the United States. We downloaded data on COVID-19 cases and deaths for each US county up through June 7, 2020, from Johns Hopkins University, Center for Systems Science and Engineering Coronavirus Resource Center. We used April-May 2020 Normalized Difference Vegetation Index (NDVI) data, to represent the greenness exposure during the initial COVID-19 outbreak in the US. We fitted negative binomial mixed models to evaluate associations of NDVI with COVID-19 incidence and mortality, adjusting for potential confounders such as county-level demographics, epidemic stage, and other environmental factors. We evaluated whether the associations were modified by population density, proportion of Black residents, median home value, and issuance of stay-at-home order. An increase of 0.1 in NDVI was associated with a 6% (95% Confidence Interval: 3%, 10%) decrease in COVID-19 incidence rate after adjustment for potential confounders. Associations with COVID-19 incidence were stronger in counties with high population density and in counties with stay-at-home orders. Greenness was not associated with COVID-19 mortality in all counties; however, it was protective in counties with higher population density. Discussion: Exposures to NDVI had beneficial impacts on county-level incidence of COVID-19 in the US and may have reduced county-level COVID-19 mortality rates, especially in densely populated counties.

Sections du résumé

BACKGROUND BACKGROUND
COVID-19 is an infectious disease that has killed more than 246,000 people in the US. During a time of social distancing measures and increasing social isolation, green spaces may be a crucial factor to maintain a physically and socially active lifestyle while not increasing risk of infection.
OBJECTIVES OBJECTIVE
We evaluated whether greenness is related to COVID-19 incidence and mortality in the United States.
METHODS METHODS
We downloaded data on COVID-19 cases and deaths for each US county up through June 7, 2020, from Johns Hopkins University, Center for Systems Science and Engineering Coronavirus Resource Center. We used April-May 2020 Normalized Difference Vegetation Index (NDVI) data, to represent the greenness exposure during the initial COVID-19 outbreak in the US. We fitted negative binomial mixed models to evaluate associations of NDVI with COVID-19 incidence and mortality, adjusting for potential confounders such as county-level demographics, epidemic stage, and other environmental factors. We evaluated whether the associations were modified by population density, proportion of Black residents, median home value, and issuance of stay-at-home order.
RESULTS RESULTS
An increase of 0.1 in NDVI was associated with a 6% (95% Confidence Interval: 3%, 10%) decrease in COVID-19 incidence rate after adjustment for potential confounders. Associations with COVID-19 incidence were stronger in counties with high population density and in counties with stay-at-home orders. Greenness was not associated with COVID-19 mortality in all counties; however, it was protective in counties with higher population density. Discussion: Exposures to NDVI had beneficial impacts on county-level incidence of COVID-19 in the US and may have reduced county-level COVID-19 mortality rates, especially in densely populated counties.

Identifiants

pubmed: 32908990
doi: 10.1101/2020.08.26.20181644
pmc: PMC7480038
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIEHS NIH HHS
ID : P30 ES000002
Pays : United States
Organisme : NIEHS NIH HHS
ID : R01 ES028033
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL150119
Pays : United States

Commentaires et corrections

Type : UpdateIn

Déclaration de conflit d'intérêts

Declaration of interest The authors declare they have no actual or potential competing financial interests.

Auteurs

Jochem O Klompmaker (JO)

Department of Environmental Health, Harvard T. H. Chan School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115.

Jaime E Hart (JE)

Department of Environmental Health, Harvard T. H. Chan School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115.
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, Massachusetts 02115.

Isabel Holland (I)

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, Massachusetts 02115.

M Benjamin Sabath (MB)

Department of Biostatistics, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, Massachusetts 02115.

Xiao Wu (X)

Department of Biostatistics, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, Massachusetts 02115.

Francine Laden (F)

Department of Environmental Health, Harvard T. H. Chan School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115.
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, Massachusetts 02115.
Department of Epidemiology, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, Boston, Massachusetts 02115.

Francesca Dominici (F)

Department of Biostatistics, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, Massachusetts 02115.

Peter James (P)

Department of Environmental Health, Harvard T. H. Chan School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115.
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Drive, Boston, Massachusetts 02215.

Classifications MeSH