Prescription Tranquilizer/Sedative Misuse Motives Across the US Population.
Journal
Journal of addiction medicine
ISSN: 1935-3227
Titre abrégé: J Addict Med
Pays: Netherlands
ID NLM: 101306759
Informations de publication
Date de publication:
Historique:
pubmed:
11
9
2020
medline:
30
6
2021
entrez:
10
9
2020
Statut:
ppublish
Résumé
Roughly 6.5 million US residents engaged in prescription tranquilizer/sedative (eg, benzodiazepines, Z-drugs) misuse in 2018, but tranquilizer/sedative misuse motives are understudied, with a need for nationally representative data and examinations of motives by age group. Our aims were to establish tranquilizer/sedative misuse motives and correlates of motives by age cohort, and whether motive-age cohort interactions existed by correlate. Data were from the 2015 to 2018 US National Survey on Drug Use and Health, with 223,520 total respondents (51.5% female); 6580 noted past-year prescription tranquilizer/sedative misuse motives (2.4% overall, 50.3% female). Correlates included substance use (eg, opioid misuse), mental (eg, suicidal ideation) and physical health variables (e.g., inpatient hospitalization). Design-based, weighted cross-tabulations and logistic regression analyses were used, including analyses of age cohort-motive interactions for each correlate. Prescription tranquilizer/sedative misuse motives varied by age group, with the highest rates of self-treatment only motives (ie, sleep and/or relax) in those 65 and older (82.7%), and the highest rates of any recreational motives in adolescents (12-17 years; 67.5%). Any tranquilizer/sedative misuse was associated with elevated odds of substance use, mental health, and physical health correlates, but recreational misuse was associated with the highest odds. Age-based interactions suggested stronger relationships between tranquilizer/sedative misuse and mental health in adults 50 and older. Any tranquilizer/sedative misuse signals a need for substance use and mental health screening, with intervention needs most acute in those with any recreational motives. Older adult tranquilizer/sedative misuse may be more driven by undertreated insomnia and anxiety/psychopathology than in younger groups.
Identifiants
pubmed: 32909984
pii: 01271255-202106000-00004
doi: 10.1097/ADM.0000000000000736
pmc: PMC7937768
mid: NIHMS1654755
doi:
Substances chimiques
Analgesics, Opioid
0
Hypnotics and Sedatives
0
Tranquilizing Agents
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
191-200Subventions
Organisme : NIDA NIH HHS
ID : R01 DA031160
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA042146
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA043691
Pays : United States
Informations de copyright
Copyright © 2020 American Society of Addiction Medicine.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest.
Références
Barrett SP, Meisner JR, Stewart SH. What constitutes prescription drug misuse? Problems and pitfalls of current conceptualizations. Curr Drug Abuse Rev 2008; 1 (3):255–262.
Substance Abuse and Mental Health Services Administration. Results From the 2018 National Survey on Drug Use and Health: Detailed Tables. Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration; 2019.
Votaw VR, Geyer R, Rieselbach MM, McHugh RK. The epidemiology of benzodiazepine misuse: a systematic review. Drug Alcohol Depend 2019; 200:95–114.
American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 updated AGS beers criteria(R) for potentially inappropriate medication use in older adults. J Am Geriatr Soc 2019; 67 (4):674–694.
Schepis TS. Age cohort differences in the nonmedical use of prescription zolpidem: findings from a nationally representative sample. Addict Behav 2014; 39 (9):1311–1317.
Schepis TS, Teter CJ, Simoni-Wastila L, McCabe SE. Prescription tranquilizer/sedative misuse prevalence and correlates across age cohorts in the US. Addict Behav 2018; 87:24–32.
Maree RD, Marcum ZA, Saghafi E, Weiner DK, Karp JF. A systematic review of opioid and benzodiazepine misuse in older adults. Am J Geriatr Psychiatry 2016; 24 (11):949–963.
Boyd CJ, West B, McCabe SE. Does misuse lead to a disorder? The misuse of prescription tranquilizer and sedative medications and subsequent substance use disorders in a U.S. longitudinal sample. Addict Behav 2018; 79:17–23.
Schepis TS, Simoni-Wastila L, McCabe SE. Prescription opioid and benzodiazepine misuse is associated with suicidal ideation in older adults. Int J Geriatr Psychiatry 2019; 34 (1):122–129.
Carey KB, Scott-Sheldon LA, Carey MP, DeMartini KS. Individual-level interventions to reduce college student drinking: a meta-analytic review. Addict Behav 2007; 32 (11):2469–2494.
Canale N, Vieno A, Santinello M, Chieco F, Andriolo S. The efficacy of computerized alcohol intervention tailored to drinking motives among college students: a quasi-experimental pilot study. Am J Drug Alcohol Abuse 2015; 41 (2):183–187.
Blevins CE, Banes KE, Stephens RS, Walker DD, Roffman RA. Change in motives among frequent cannabis-using adolescents: predicting treatment outcomes. Drug Alcohol Depend 2016; 167:175–181.
Boyd CJ, McCabe SE, Cranford JA, Young A. Adolescents’ motivations to abuse prescription medications. Pediatrics 2006; 118 (6):2472–2480.
McCabe SE, Cranford JA. Motivational subtypes of nonmedical use of prescription medications: results from a national study. J Adolesc Health 2012; 51 (5):445–452.
Silva K, Kecojevic A, Lankenau SE. Perceived drug use functions and risk reduction practices among high-risk nonmedical users of prescription drugs. J Drug Issues 2013; 43 (4):483–496.
McCabe SE, Boyd CJ, Teter CJ. Subtypes of nonmedical prescription drug misuse. Drug Alcohol Depend 2009; 102 (1–3):63–70.
Nattala P, Leung KS, Abdallah AB, Murthy P, Cottler LB. Motives and simultaneous sedative-alcohol use among past 12-month alcohol and nonmedical sedative users. Am J Drug Alcohol Abuse 2012; 38 (4):359–364.
Rigg KK, Ibanez GE. Motivations for non-medical prescription drug use: a mixed methods analysis. J Subst Abuse Treat 2010; 39 (3):236–247.
Stein MD, Kanabar M, Anderson BJ, Lembke A, Bailey GL. Reasons for benzodiazepine use among persons seeking opioid detoxification. J Subst Abuse Treat 2016; 68:57–61.
Fatséas M, Lavie E, Denis C, Auriacombe M. Self-perceived motivation for benzodiazepine use and behavior related to benzodiazepine use among opiate-dependent patients. J Subst Abuse Treat 2009; 37 (4):407–411.
Grant BF, Chu A, Sigman R, et al. Source and Accuracy Statement: National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III). Rockville, MD: National Institute on Alcohol Abuse and Alcoholism; 2014.
Center for Behavioral Health Statistics and Quality. 2016 National Survey on Drug Use and Health: Methodological Resource Book (Section 8, Data Collection Final Report). Rockville, MD: Substance Abuse and Mental Health Services Administration; 2017.
McCabe SE, Boyd CJ, Cranford JA, Teter CJ. Motives for nonmedical use of prescription opioids among high school seniors in the United States: self-treatment and beyond. Arch Pediatr Adolesc Med 2009; 163 (8):739–744.
National Institute of Alcohol Abuse and Alcoholism. NIAAA Newsletter, Winter 2004. Bethesda, MD: Office of Research Translation and Communications, NIAAA; 2004.
Kessler RC, Barker PR, Colpe LJ, et al. Screening for serious mental illness in the general population. Arch Gen Psychiatry 2003; 60 (2):184–189.
Center for Behavioral Health Statistics and Quality. 2016 National Survey on Drug Use and Health: Methodological Resource Book (Section 13: Statistical Inference Report) . Rockville, MD: Substance Abuse and Mental Health Services Administration; 2017.
Schepis TS, Wastila L, Ammerman B, McCabe VV, McCabe SE. Prescription opioid misuse motives in US older adults. Pain Med . 2020. In Press.
Cheetham A, Allen NB, Yucel M, Lubman DI. The role of affective dysregulation in drug addiction. Clin Psychol Rev 2010; 30 (6):621–634.
Statistics Canada. Table 13-10-00-04: Perceived life stress, by age group. Available at: https://www150.statcan.gc.ca/t1/tbl1/en/tv.action?pid=1310009604 . Accessed April 8, 2020.
Health Resources and Services Administration, Maternal and Child Health Bureau. The Health and Well-Being of Children: A Portrait of States and the Nation, 2011–2012. Rockville, Maryland: U.S. Department of Health and Human Services; 2014.
Muller CP, Schumann G. Drugs as instruments: a new framework for non-addictive psychoactive drug use. Behav Brain Sci 2011; 34 (6):293–310.
Spoth R, Trudeau L, Redmond C, Shin C. Replicating and extending a model of effects of universal preventive intervention during early adolescence on young adult substance misuse. J Consult Clin Psychol 2016; 84 (10):913–921.
Spoth R, Trudeau L, Shin C, et al. Longitudinal effects of universal preventive intervention on prescription drug misuse: three randomized controlled trials with late adolescents and young adults. Am J Public Health 2013; 103 (4):665–672.
Spoth R, Trudeau L, Shin C, Redmond C. Long-term effects of universal preventive interventions on prescription drug misuse. Addiction 2008; 103 (7):1160–1168.
O’Malley PM, Bachman JG, Johnston LD. Reliability and consistency in self-reports of drug use. Internati J Addict 1983; 18:805–824.
Johnston LD, O’Malley PM. Issues of validity and population coverage in student surveys of drug use. NIDA Res Monogr 1985; 57:31–54.
Center for Behavioral Health Statistics and Quality. National Survey on Drug Use and Health (NSDUH): Summary of methodological studies, 1971–2014. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2014.
Cunningham D, Flicker L, Murphy J, Aldworth J, Myers S, Kennet J. Incidence and Impact of Controlled Access Situations on Nonresponse. Miami Beach, FL: American Association for Public Opinion Research 60th Annual Conference; 2015.