Ab Interno Canaloplasty in Open-angle Glaucoma Patients Combined With In Vivo Trypan Blue Aqueous Venography.
Aged
Aqueous Humor
/ physiology
Coloring Agents
/ administration & dosage
Female
Follow-Up Studies
Glaucoma, Open-Angle
/ physiopathology
Humans
Intraocular Pressure
/ physiology
Male
Middle Aged
Phlebography
Retrospective Studies
Tonometry, Ocular
Trabeculectomy
/ methods
Treatment Outcome
Trypan Blue
/ administration & dosage
Viscosupplements
Journal
Journal of glaucoma
ISSN: 1536-481X
Titre abrégé: J Glaucoma
Pays: United States
ID NLM: 9300903
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
pubmed:
11
9
2020
medline:
27
2
2021
entrez:
10
9
2020
Statut:
ppublish
Résumé
To demonstrate canalogram patterns observed when trypan blue tracer is combined with oculoviscoelastic device during ab interno canaloplasty, and discuss surgical results and potential implications for diagnosis, prognosis, and treatment. This is a retrospective small case series study. The authors performed this procedure on 5 patients with informed consent with 4 to 18 months of follow-up. All procedures have been complication free. The average preoperative intraocular pressure was 16.4 mm Hg with an average number of topical glaucoma medications being equal to 3.6. Postoperatively, the average intraocular pressure for the group was reduced to 13 mm Hg with a concurrent drop in the average number of topical medications used equaling 1.8. Currently, there are limited practical options to evaluate the patency of the aqueous outflow system in our patients. The primary purpose of this paper is to describe canalogram patterns observed during ab interno canaloplasty with trypan blue. This technique may allow us to further our understanding of the aqueous outflow system and its role in the underlying pathophysiology of glaucoma. Further research is required to evaluate the prognostic and diagnostic significance of this technique.
Identifiants
pubmed: 32910008
doi: 10.1097/IJG.0000000000001656
pii: 00061198-202012000-00016
doi:
Substances chimiques
Coloring Agents
0
Viscosupplements
0
Trypan Blue
I2ZWO3LS3M
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e130-e134Références
Tham Y, Li XL, Wong TY, et al. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014;121:2081–2090.
The AGIS Investigators. The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration. Am J Ophthalmol. 2000;130:429–440.
Saheb H, Ahmed IIK. Micro-invasive glaucoma surgery: current perspectives and future directions. Curr Opin Ophthalmol. 2012;23:96–104.
Godfrey DG, Fellman RL, Neelakantan A. Canal surgery in adult glaucomas. Curr Opin Ophthalmol. 2009;20:116–121.
Korber N. Ab interno canaloplasty for the treatment of glaucoma: a case series study. Spektrum Augenheilkd. 2016;32:223–227.
Brusini P. Canaloplasty in open-angle glaucoma surgery: a four year follow up. ScientificWorldJournal. 2014:469609.
Lewis RA, Wolff KV, Tetz M, et al. Canaloplasty: three-year results of circumferential viscodilation and tensioning of Schlemm canal using a microcatheter to treat open-angle glaucoma. J Cataract Refract Surg. 2011;37:682–690.
Grieshaber MC, Fraenkl S, Schoetzau A, et al. Circumferential viscocanalostomy and suture canal distension (Canaloplasty) for Whites with open-angle glaucoma. J Glaucoma. 2011;20:298–302.
Xie M, Zheng Y, Huang L, et al. Experimental circumferential canaloplasty with a new Schlemm canal microcatheter. Int J Ophthalmol. 2018;11:1–5.
Khaimi MA, Dvorak JD, Ding K. An analysis of 3-year outcomes following canaloplasty for the treatment of open angle glaucoma. J Ophthalmol. 2017. Doi:10.1155/2017/2904272.
doi: 10.1155/2017/2904272
Khaimi MA. Canaloplasty: a minimally invasive and maximally effective glaucoma treatment. J Ophthalmol. 2015:485065.
Harvey BJ, Khaimi MA. A review of canaloplasty. Saudi J Ophthalmol. 2011;25:329–336.
Grieshaber MC. Viscocanalostomy and canaloplasty: ab externo Schlemm’s canal surgery. Dev Ophthalmol. 2017;59:113–126.
Grieshaber MC. Stegmann canal expander for canaloplasty: a novel technique. Eur J Ophthalmol. 2018;28:472–478.
Grieshaber MC, Schoetzau A, Grieshaber HR, et al. Canaloplasty with Stegmann canal expander for primary open-angle glaucoma. Acta Ophthalmol. 2017;95:503–508.
Zeppa I, Ambrosone L, Guerra G, et al. In vivo near infrared fluorescence imaging of aqueous humor outflow structures. J Ophthalmol. 2016:8706564.
Grieshaber MC, Pienaar A, Olivier J, et al. Clinical evaluation of the aqueous outflow system in primary open-angle glaucoma for canaloplasty. Invest Ophthalmol Vis Sci. 2010;51:1498–1504.
Laroche D, Nortey A, Ng C. A novel use of trypan blue during canalicular glaucoma surgery to identify aqueous outflow to episcleral and intrascleral veins. J Glaucoma. 2018;27:e158–e161.
Fellman RL, Grover DS. Episcleral venous fluid wave: intraoperative evidence for patency of the conventional outflow system. J Glaucoma. 2014;23:347–350.
Huang AS, Penteado RC, Saha SK, et al. Fluorescein aqueous angiography in live normal human eyes. J Glaucoma. 2018;27:957–964.
Johnstone MA. The aqueous outflow system as a mechanical pump: evidence from examination of tissue and aqueous movement in human and non-human primates. J Glaucoma. 2004;13:421–438.