Positive Effects of Local Botulinum Toxin Injection and Colchicine for Complicated Chronic Recurrent Parotitis: A Case Report.
Journal
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
ISSN: 1531-5053
Titre abrégé: J Oral Maxillofac Surg
Pays: United States
ID NLM: 8206428
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
23
06
2020
revised:
07
08
2020
accepted:
07
08
2020
pubmed:
11
9
2020
medline:
10
2
2021
entrez:
10
9
2020
Statut:
ppublish
Résumé
Chronic recurrent parotitis (CRP) is a rare affliction of unknown cause characterized by recurrent episodes of unilateral or bilateral nonobstructive and nonsuppurative inflammation of the parotid glands. Management of CRP is not standardized, and attempts at treatment often fail. We report a case of a 29-year-old female patient with CRP for 13 years, with recurrent acute episodes, complicated with a collection and cutaneous fistula, refractory to repeated courses of corticosteroids and antibiotics. Injections of botulinum toxin in the parotid gland and maintenance treatment with oral colchicine lead to a rapid and sustained improvement. Local botulinum toxin injections associated with colchicine might represent a safe and noninvasive treatment of CRP. The possible beneficial effect of colchicine could be an argument for auto-inflammatory participation in the pathogenesis of CRP.
Identifiants
pubmed: 32910892
pii: S0278-2391(20)30996-4
doi: 10.1016/j.joms.2020.08.008
pii:
doi:
Substances chimiques
Botulinum Toxins
EC 3.4.24.69
Botulinum Toxins, Type A
EC 3.4.24.69
Colchicine
SML2Y3J35T
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
383-388Informations de copyright
Copyright © 2020 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.