Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses.
Adolescent
Adult
Aged
Aged, 80 and over
COVID-19
/ diagnosis
COVID-19 Nucleic Acid Testing
Child
Child, Preschool
Coronavirus Infections
/ diagnosis
Disease Progression
Female
Humans
Infant
Infant, Newborn
Influenza B virus
/ isolation & purification
Influenza, Human
/ virology
Male
Middle Aged
Pandemics
Respiratory Syncytial Virus Infections
/ virology
Respiratory Syncytial Viruses
/ isolation & purification
SARS-CoV-2
/ isolation & purification
Serologic Tests
/ methods
Switzerland
/ epidemiology
Viral Load
/ statistics & numerical data
COVID-19
Cycle threshold
Diagnostic
RT-PCR
SARS-CoV-2
Viral load
Journal
Microbes and infection
ISSN: 1769-714X
Titre abrégé: Microbes Infect
Pays: France
ID NLM: 100883508
Informations de publication
Date de publication:
Historique:
received:
02
06
2020
revised:
26
08
2020
accepted:
27
08
2020
pubmed:
11
9
2020
medline:
7
1
2021
entrez:
10
9
2020
Statut:
ppublish
Résumé
RT-PCRs to detect SARS-CoV-2 RNA is key to manage the COVID-19 pandemic. We analyzed SARS-CoV-2 viral loads from 22'323 RT-PCR results according to samples types, gender, age, and health units. Viral load did not show any difference across age and appears to be a poor predictor of disease outcome. SARS-CoV-2 viral load showed similar high viral loads than the one observed for RSV and influenza B. The importance of viral load to predict contagiousness and to assess disease progression is discussed.
Identifiants
pubmed: 32911086
pii: S1286-4579(20)30151-9
doi: 10.1016/j.micinf.2020.08.004
pmc: PMC7476607
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
617-621Informations de copyright
Copyright © 2020. Published by Elsevier Masson SAS.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare to have no conflict of interest.
Références
Future Microbiol. 2016;11(3):403-25
pubmed: 27028061
Lancet. 2020 Feb 15;395(10223):470-473
pubmed: 31986257
Euro Surveill. 2020 Jan;25(3):
pubmed: 31992387
Lancet. 2020 May 2;395(10234):1417-1418
pubmed: 32325026
Lancet Respir Med. 2020 May;8(5):430-432
pubmed: 32272081
Clin Infect Dis. 2017 Jun 15;64(suppl_3):S337-S346
pubmed: 28575373
N Engl J Med. 2020 Apr 23;382(17):1663-1665
pubmed: 32187458
Clin Infect Dis. 2020 Nov 19;71(16):2252-2254
pubmed: 32435816
J Clin Microbiol. 2020 Apr 23;58(5):
pubmed: 32132196
N Engl J Med. 2020 Mar 19;382(12):1177-1179
pubmed: 32074444
MMWR Morb Mortal Wkly Rep. 2020 Apr 03;69(13):377-381
pubmed: 32240128
N Engl J Med. 2020 May 28;382(22):2081-2090
pubmed: 32329971
Nat Med. 2020 May;26(5):672-675
pubmed: 32296168
Lancet Infect Dis. 2020 May;20(5):565-574
pubmed: 32213337
J Clin Microbiol. 2020 May 26;58(6):
pubmed: 32277022
Nat Rev Immunol. 2020 Jun;20(6):363-374
pubmed: 32346093
JAMA Pediatr. 2020 Sep 1;174(9):882-889
pubmed: 32320004
Int J Infect Dis. 2019 Mar;80:92-97
pubmed: 30634045
Lancet Infect Dis. 2020 Aug;20(8):911-919
pubmed: 32353347
Lancet. 2003 May 24;361(9371):1767-72
pubmed: 12781535
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
J Infect Dis. 2015 Nov 1;212(9):1420-8
pubmed: 25883385