Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
/ genetics
Disease Progression
Female
Gene Rearrangement
Humans
In Situ Hybridization, Fluorescence
Lymphoma, Large B-Cell, Diffuse
/ genetics
Male
Middle Aged
Progression-Free Survival
Proto-Oncogene Proteins c-bcl-2
/ genetics
Proto-Oncogene Proteins c-bcl-6
/ genetics
Recurrence
Young Adult
cytogenetics
lymphoma
molecular
pathology
Journal
Journal of clinical pathology
ISSN: 1472-4146
Titre abrégé: J Clin Pathol
Pays: England
ID NLM: 0376601
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
18
05
2020
revised:
08
07
2020
accepted:
10
08
2020
pubmed:
12
9
2020
medline:
5
10
2021
entrez:
11
9
2020
Statut:
ppublish
Résumé
Diffuse large B-cell lymphoma (DLBCL) is the most common type of aggressive non-Hodgkin's lymphoma that represents a heterogeneous group of disease that is differentially characterised by clinical, molecular and cytogenetic features. We collected tumour tissue and clinical data from 97 DLBCL and used interphase fluorescence in situ hybridisation (FISH) with break-apart probe to characterise 19 of 97 (19,6%) cases of DLBCL had atypical/ unbalanced gene rearrangements (14 involving We showed that patients with DLBCL with
Identifiants
pubmed: 32912960
pii: jclinpath-2020-206767
doi: 10.1136/jclinpath-2020-206767
doi:
Substances chimiques
BCL2 protein, human
0
BCL6 protein, human
0
Biomarkers, Tumor
0
Proto-Oncogene Proteins c-bcl-2
0
Proto-Oncogene Proteins c-bcl-6
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
650-656Informations de copyright
© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.