Pulmonary aspergillosis in critically ill patients with Coronavirus Disease 2019 (COVID-19).
Aspergillus
COVID-19
COVID-19 associated pulmonary aspergillosis (CAPA)
acute respiratory distress syndrome
intensive care unit
pulmonary aspergillosis
Journal
Medical mycology
ISSN: 1460-2709
Titre abrégé: Med Mycol
Pays: England
ID NLM: 9815835
Informations de publication
Date de publication:
04 Jan 2021
04 Jan 2021
Historique:
received:
28
05
2020
accepted:
11
08
2020
revised:
04
08
2020
pubmed:
12
9
2020
medline:
13
1
2021
entrez:
11
9
2020
Statut:
ppublish
Résumé
Occurrence of putative invasive pulmonary aspergillosis was screened in 153 consecutive adult intensive care unit (ICU) patients with respiratory samples addressed for mycological diagnosis during a 6-week period at the emergence of coronavirus disease 2019 (COVID-19) pandemic. Positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) was observed for 106 patients (69.3%). Nineteen of them (17.9%) with positive Aspergillus results were considered as having putative invasive pulmonary aspergillosis. These observations underline the risk of pulmonary aspergillosis in COVID-19 patients, even in patients not previously known to be immunosuppressed, advocating active search for Aspergillus infection and prompt antifungal treatment. Standardized surveillance protocols and updated definitions for ICU putative invasive pulmonary aspergillosis are needed. Adult ICU patients with respiratory samples addressed for mycological diagnosis were screened during the emergence of COVID-19 pandemic. Positive SARS-CoV-2 PCR was observed for 106 patients, nineteen of them (17.9%) having aspergillosis. This underlines the risk of aspergillosis in COVID-19 patients.
Identifiants
pubmed: 32914189
pii: 5903915
doi: 10.1093/mmy/myaa078
pmc: PMC7499748
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
110-114Informations de copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.
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