Management of Skull Base Metastases.


Journal

Neurosurgery clinics of North America
ISSN: 1558-1349
Titre abrégé: Neurosurg Clin N Am
Pays: United States
ID NLM: 9008004

Informations de publication

Date de publication:
Oct 2020
Historique:
entrez: 14 9 2020
pubmed: 15 9 2020
medline: 20 7 2021
Statut: ppublish

Résumé

Autopsy studies suggest that skull base metastases are likely underrecognized in patients with cancer. Patients frequently present with one or a combination of skull base clinical syndromes that manifest as pain or cranial neuropathy. Once a skull base metastasis is suspected, establishing a histologic diagnosis, dedicated imaging, and restaging (if appropriate) are the first steps in management. A multidisciplinary approach should then be used to identify the optimal histology-based treatment strategy, taking into account the burden of systemic disease. Finally, definitive treatment may include one or a combination of surgical management, radiation therapy, or chemotherapy."

Identifiants

pubmed: 32921360
pii: S1042-3680(20)30065-6
doi: 10.1016/j.nec.2020.06.013
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

659-666

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose. The authors received no funding.

Auteurs

Gautam U Mehta (GU)

Division of Neurosurgery, House Clinic, 2100 West 3rd Street, Suite 111, Los Angeles, CA 90057, USA. Electronic address: https://twitter.com/GautamMehtaMD.

Shaan M Raza (SM)

Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, Room FC7.200, Unit 442, Houston, TX 77030-4009, USA. Electronic address: smraza@mdanderson.org.

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Classifications MeSH