Environmental stress influences mitochondrial metabolism in vascular cells: consequences for angiogenesis.
ROS
capillary
endothelium
signalling
Journal
Vascular biology (Bristol, England)
ISSN: 2516-5658
Titre abrégé: Vasc Biol
Pays: England
ID NLM: 101763329
Informations de publication
Date de publication:
2019
2019
Historique:
received:
29
08
2019
accepted:
01
10
2019
entrez:
14
9
2020
pubmed:
15
9
2020
medline:
15
9
2020
Statut:
epublish
Résumé
While the important and varied roles that vascular cells play in both health and disease is well recognised, the focus on potential therapeutic targets continually shifts as new players emerge. Here, we outline how mitochondria may be viewed as more than simply energy-generating organelles, but instead as important sentinels of metabolic health and effectors of appropriate responses to physiological challenges.
Identifiants
pubmed: 32923962
doi: 10.1530/VB-19-0018
pii: VB-19-0018
pmc: PMC7439850
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
H111-H116Subventions
Organisme : British Heart Foundation
ID : PG/14/15/30691
Pays : United Kingdom
Informations de copyright
© 2019 The authors.
Déclaration de conflit d'intérêts
The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of this review.
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