The Molecular Effects of a High Fat Diet on Endometrial Tumour Biology.

endometrial cancer obesity transcriptomics

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
10 Sep 2020
Historique:
received: 13 08 2020
revised: 30 08 2020
accepted: 02 09 2020
entrez: 15 9 2020
pubmed: 16 9 2020
medline: 16 9 2020
Statut: epublish

Résumé

We sought to validate the BDII/Han rat model as a model for diet-induced obesity in endometrial cancer (EC) and determine if transcriptomic changes induced by a high fat diet (HFD) in an EC rat model can be used to identify novel biomarkers in human EC. Nineteen BDII/Han rats were included. Group A (

Identifiants

pubmed: 32927694
pii: life10090188
doi: 10.3390/life10090188
pmc: PMC7554710
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Cancer. 2017 Mar 1;123(5):802-813
pubmed: 28061006
Mol Clin Oncol. 2017 Aug;7(2):301-307
pubmed: 28781807
Bioinformatics. 2018 Sep 1;34(17):i884-i890
pubmed: 30423086
J Natl Cancer Inst. 2014 Sep 10;106(9):
pubmed: 25214561
Radiother Oncol. 2015 Dec;117(3):559-81
pubmed: 26683800
Cell Death Dis. 2019 Mar 20;10(4):276
pubmed: 30894514
Mol Cell Biol. 2014 Jun;34(12):2135-46
pubmed: 24687854
Genes Chromosomes Cancer. 2001 Aug;31(4):345-56
pubmed: 11433525
Cancer Res. 1998 Aug 1;58(15):3254-8
pubmed: 9699651
Sci Rep. 2019 Jan 29;9(1):845
pubmed: 30696915
Mol Cell Biol. 1999 Oct;19(10):7158-67
pubmed: 10490651
J Clin Oncol. 2013 Jul 10;31(20):2607-18
pubmed: 23733771
Nat Methods. 2017 Jul;14(7):687-690
pubmed: 28581496
PLoS One. 2017 Dec 27;12(12):e0189514
pubmed: 29281661
Cell Rep. 2018 Feb 20;22(8):2133-2145
pubmed: 29466739
Endocr Relat Cancer. 2003 Mar;10(1):23-42
pubmed: 12653669
Nat Biotechnol. 2016 May;34(5):525-7
pubmed: 27043002
Exp Neurol. 2003 Nov;184(1):153-61
pubmed: 14637088
CA Cancer J Clin. 2018 Jan;68(1):7-30
pubmed: 29313949
Prostate. 2018 Aug;78(11):819-829
pubmed: 29659051
Nucleic Acids Res. 2015 Apr 20;43(7):e47
pubmed: 25605792
Endocr Relat Cancer. 2009 Mar;16(1):99-111
pubmed: 19075038
Oncology. 1995 Jul-Aug;52(4):319-25
pubmed: 7777247
Genes Chromosomes Cancer. 2005 Oct;44(2):139-53
pubmed: 15942940
J Natl Cancer Inst. 1987 Jun;78(6):1245-51
pubmed: 3473261
N Engl J Med. 2016 Aug 25;375(8):794-8
pubmed: 27557308
Endocr Relat Cancer. 2019 Jan 1;26(1):31-46
pubmed: 30121621
Cancer Res. 1998 Jun 15;58(12):2500-3
pubmed: 9635567
Exp Toxicol Pathol. 2004 Jul;55(6):433-49
pubmed: 15384249
Cancer Sci. 2012 Apr;103(4):747-55
pubmed: 22321069
Exp Toxicol Pathol. 2003 Sep;55(2-3):91-106
pubmed: 14620530
Gynecol Oncol. 2019 Jun;153(3):487-495
pubmed: 30922603
J Exp Clin Cancer Res. 2019 Aug 16;38(1):361
pubmed: 31419991
Cancer Genet Cytogenet. 2001 Jun;127(2):118-27
pubmed: 11425450
Cell Rep. 2014 Jul 24;8(2):460-9
pubmed: 25017071
Oncotarget. 2016 Dec 26;8(32):52432-52444
pubmed: 28881741
Cancer Res. 2008 Dec 1;68(23):9735-45
pubmed: 19047152
Comput Struct Biotechnol J. 2020 Mar 19;18:668-675
pubmed: 32257050
BMC Cancer. 2018 Jul 20;18(1):750
pubmed: 30029633
Nature. 2013 May 2;497(7447):67-73
pubmed: 23636398
Int J Gynecol Pathol. 2004 Jul;23(3):234-40
pubmed: 15213599

Auteurs

Michael Wilkinson (M)

Department of Gynaecological Oncology, UCD School of Medicine, Mater Misericordiae Universtity Hospital, Eccles Street, Dublin 7, D07 AX57 Dublin, Ireland.
UCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.

Piriyah Sinclair (P)

UCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.

Ludmilla Dellatorre-Teixeira (L)

UCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.

Patrick Swan (P)

UCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.

Eoin Brennan (E)

UCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.

Bruce Moran (B)

Department of Pathology, St Vincent's University Hospital, Elm Park, Dublin 4, D04 YN63 Dublin, Ireland.

Dirk Wedekind (D)

Biomedical Facility, Hanover Medical School, 30625 Hanover, Germany.

Paul Downey (P)

Department of Pathology, National Maternity Hospital, Holles Street, Dublin 2, D02 YH21 Dublin, Ireland.

Kieran Sheahan (K)

Department of Pathology, St Vincent's University Hospital, Elm Park, Dublin 4, D04 YN63 Dublin, Ireland.

Emer Conroy (E)

Cancer Biology and Therapeutic Laboratory, UCD School of Biomolecular and Biomedical Science Ireland, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.

William M Gallagher (WM)

Cancer Biology and Therapeutic Laboratory, UCD School of Biomolecular and Biomedical Science Ireland, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.

Neil Docherty (N)

UCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.

Carel le Roux (CL)

UCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
Department of Pathology, St Vincent's University Hospital, Elm Park, Dublin 4, D04 YN63 Dublin, Ireland.

Donal J Brennan (DJ)

Department of Gynaecological Oncology, UCD School of Medicine, Mater Misericordiae Universtity Hospital, Eccles Street, Dublin 7, D07 AX57 Dublin, Ireland.
UCD Diabetes Complications Research Centre, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
Cancer Biology and Therapeutic Laboratory, UCD School of Biomolecular and Biomedical Science Ireland, UCD Conway Institute, University College Dublin, D14 NN96 Dublin, Ireland.
Systems Biology Ireland, UCD School of Medicine, Belfield, Dublin 4, D14 NN96 Dublin, Ireland.

Classifications MeSH