Population-based analysis on the effect of nodal and distant metastases in sinonasal adenocarcinoma.
SEER database
distant metastases
epidemiology
nasal cavity
nodal metastases
paranasal sinuses
sinonasal adenocarcinoma
sinonasal malignancy
Journal
Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
06
05
2020
revised:
19
07
2020
accepted:
26
08
2020
pubmed:
16
9
2020
medline:
22
6
2021
entrez:
15
9
2020
Statut:
ppublish
Résumé
Minimal information has been reported on the effect of distant and nodal metastases at the time of diagnosis on survival in patients with sinonasal adenocarcinoma (SNAC). The Surveillance, Epidemiology, and End Results database was utilized to compare overall survival (OS) and disease-specific survival (DSS). Of the 325 patients with SNAC identified, 5-year and 10-year OS for all included patients was 64% and 58%, respectively. On multivariate analysis, the presence of distant metastases (P < .0001), maxillary and frontal sinus primary tumors (P = .0042, P = .0006), and increasing age (P = .007) were risk factors for worsened DSS. The presence of regional spread to multiple cervical nodal basins (OS RR 3.26, P = .002; DSS RR 2.51, P = .013) and a single nodal basin (DSS RR 2.19, P = .046) was associated with worsened survival compared to no regional spread. Survival in SNAC was significantly worsened with increasing age, tumor site of origin, and distant metastatic disease.
Sections du résumé
BACKGROUND
Minimal information has been reported on the effect of distant and nodal metastases at the time of diagnosis on survival in patients with sinonasal adenocarcinoma (SNAC).
METHODS
The Surveillance, Epidemiology, and End Results database was utilized to compare overall survival (OS) and disease-specific survival (DSS).
RESULTS
Of the 325 patients with SNAC identified, 5-year and 10-year OS for all included patients was 64% and 58%, respectively. On multivariate analysis, the presence of distant metastases (P < .0001), maxillary and frontal sinus primary tumors (P = .0042, P = .0006), and increasing age (P = .007) were risk factors for worsened DSS. The presence of regional spread to multiple cervical nodal basins (OS RR 3.26, P = .002; DSS RR 2.51, P = .013) and a single nodal basin (DSS RR 2.19, P = .046) was associated with worsened survival compared to no regional spread.
CONCLUSION
Survival in SNAC was significantly worsened with increasing age, tumor site of origin, and distant metastatic disease.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
128-136Informations de copyright
© 2020 Wiley Periodicals LLC.
Références
Llorente JL, López F, Suárez C, Hermsen MA. Sinonasal carcinoma: clinical, pathological, genetic and therapeutic advances. Nat Rev Clin Oncol. 2014;11:460-472. https://doi.org/10.1038/nrclinonc.2014.97.
Turner JH, Reh DD. Incidence and survival in patients with sinonasal cancer: a historical analysis of population-based data. Head Neck. 2012;34(6):877-885. https://doi.org/10.1002/hed.21830.
Leivo I. Sinonasal adenocarcinoma: update on classification, immunophenotype and molecular features. Head Neck Pathol. 2016;10(1):68-74. https://doi.org/10.1007/s12105-016-0694-9.
Kılıç S, Samarrai R, Kılıç SS, Mikhael M, Baredes S, Eloy JA. Incidence and survival of sinonasal adenocarcinoma by site and histologic subtype. Acta Otolaryngol. 2018;138(4):415-421. https://doi.org/10.1080/00016489.2017.1401229.
Shay A, Ganti A, Raman A, et al. Survival in low-grade and high-grade sinonasal adenocarcinoma: a national cancer database analysis. Laryngoscope. 2020;130:E1-E10. https://doi.org/10.1002/lary.28052.
D'Aguillo CM, Kanumuri VV, Khan MN, et al. Demographics and survival trends of sinonasal adenocarcinoma from 1973 to 2009. Int Forum Allergy Rhinol. 2014;4(9):771-776. https://doi.org/10.1002/alr.21342.
Jain S, Li Y, Kuan EC, Tajudeen BA, Batra PS. Prognostic factors in paranasal sinus squamous cell carcinoma and adenocarcinoma: a SEER database analysis. J Neurol Surg B Skull Base. 2019;80(3):258-263. https://doi.org/10.1055/s-0038-1669420.
Choussy O, Ferron C, Védrine PO, et al. Adenocarcinoma of ethmoid: a GETTEC retrospective multicenter study of 418 cases. Laryngoscope. 2008;118(3):437-443. https://doi.org/10.1097/MLG.0b013e31815b48e3.
Bhayani MK, Yilmaz T, Sweeney A, et al. Sinonasal adenocarcinoma: a 16-year experience at a single institution. Head and Neck. 2014;36:1490-1496. https://doi.org/10.1002/hed.23485.
Chen MM, Roman SA, Sosa JA, Judson BL. Predictors of survival in sinonasal adenocarcinoma. J Neurol Surg B Skull Base. 2015;76(3):208-213. https://doi.org/10.1055/s-0034-1543995.
Low CM, Price DL, Moore EJ, et al. Nodal and distant metastases in sinonasal mucosal melanoma: a population-based analysis. Laryngoscope. 2019;130:622-627. https://doi.org/10.1002/lary.28065.
Kuan EC, Nasser HB, Carey RM, et al. A population-based analysis of nodal metastases in esthesioneuroblastomas of the sinonasal tract. Laryngoscope. 2019;129(5):1025-1029. https://doi.org/10.1002/lary.27301.
Ahn PH, Mitra N, Alonso-Basanta M, et al. Risk of lymph node metastasis and recommendations for elective nodal treatment in squamous cell carcinoma of the nasal cavity and maxillary sinus: a SEER analysis. Acta Oncol. 2016;55(9-10):1107-1114. https://doi.org/10.1080/0284186X.2016.1216656.
Ahn PH, Mitra N, Alonso-Basanta M, et al. Nodal metastasis and elective nodal level treatment in sinonasal small-cell and sinonasal undifferentiated carcinoma: a surveillance, epidemiology and end results analysis. Br J Radiol. 2016;89(1058):20150488. https://doi.org/10.1259/bjr.20150488.
Number of persons by race and hispanic ethnicity for SEER participants-SEER Registries. https://seer.cancer.gov/registries/data.html. Accessed November 4, 2019.
Kilic R, Ozdek A, Felek S, Safak MA, Samim E. A case presentation of bilateral simultaneous Bell's palsy. Am J Otolaryngol. 2003;24(4):271-273.
De Gabory L, Maunoury A, Maurice-Tison S, et al. Long-term single-center results of management of ethmoid adenocarcinoma: 95 patients over 28 years. Ann Surg Oncol. 2010;17(4):1127-1134. https://doi.org/10.1245/s10434-010-0933-3.
Michel J, Radulesco T, Penicaud M, Mancini J, Dessi P. Sinonasal adenocarcinoma: clinical outcomes and predictive factors. Int J Oral Maxillofac Surg. 2017;46(4):422-427. https://doi.org/10.1016/j.ijom.2016.11.018.
Cantù G, Bimbi G, Miceli R, et al. Lymph node metastases in malignant tumors of the paranasal sinuses: prognostic value and treatment. Arch Otolaryngol Head Neck Surg. 2008;134(2):170-177. https://doi.org/10.1001/archoto.2007.30.
Le QT, Fu KK, Kaplan MJ, Terris DJ, Fee WE, Goffinet DR. Lymph node metastasis in maxillary sinus carcinoma. Int J Radiat Oncol Biol Phys. 2000;46(3):541-549. https://doi.org/10.1016/s0360-3016(99)00453-8.
Myers LL, Nussenbaum B, Bradford CR, Teknos TN, Esclamado RM, Wolf GT. Paranasal sinus malignancies: an 18-year single institution experience. Laryngoscope. 2002;112(11):1964-1969. https://doi.org/10.1097/00005537-200211000-00010.
Caselhos S, Ferreira C, Jácome M, Monteiro E. Liver metastasis of ethmoid sinus adenocarcinoma. Eur Ann Otorhinolaryngol Head Neck Dis. 2015;132(3):157-159. https://doi.org/10.1016/j.anorl.2014.07.006.