Field evaluation of a mobile biosafety laboratory in Senegal to strengthen rapid disease outbreak response and monitoring.

MBS-Lab Senegal field deployment mobile biosafety laboratory outbreak point-of-care

Journal

African journal of laboratory medicine
ISSN: 2225-2002
Titre abrégé: Afr J Lab Med
Pays: South Africa
ID NLM: 101603205

Informations de publication

Date de publication:
2020
Historique:
received: 25 04 2019
accepted: 29 05 2020
entrez: 16 9 2020
pubmed: 17 9 2020
medline: 17 9 2020
Statut: epublish

Résumé

Past and recent outbreaks have highlighted the vulnerability of humans to infectious diseases, which represent serious economic and health security threats. A paradigm shift in the management of sanitary crises is urgently needed. Based on lessons from the 2014 Ebola outbreak, the Praesens Foundation has developed an all-terrain mobile biosafety laboratory (MBS-Lab) for effective field diagnostics capabilities. The aim of the study was to train African teams and run a field evaluation of the MBS-Lab, including robustness, technical and operational sustainability, biosafety, connectivity, turn-around times for testing and result delivery. The MBS-Lab was deployed in Senegal in October 2017 for a six-month field assessment under various ecological conditions and was mobilised during the dengue outbreaks in 2017 and 2018. The MBS-Lab can be considered an off-grid solution that addresses field challenges with regard to working conditions, mobility, deployment, environment and personnel safety. Blood ( The MBS-Lab is an innovative solution for outbreak response, even in remote areas. The study demonstrated successful local ownership and community engagement. The MBS-Lab can also be considered an open mobile healthcare platform that offers various opportunities for field-deployable, point-of-care technologies for surveillance programmes.

Sections du résumé

BACKGROUND BACKGROUND
Past and recent outbreaks have highlighted the vulnerability of humans to infectious diseases, which represent serious economic and health security threats. A paradigm shift in the management of sanitary crises is urgently needed. Based on lessons from the 2014 Ebola outbreak, the Praesens Foundation has developed an all-terrain mobile biosafety laboratory (MBS-Lab) for effective field diagnostics capabilities.
OBJECTIVE OBJECTIVE
The aim of the study was to train African teams and run a field evaluation of the MBS-Lab, including robustness, technical and operational sustainability, biosafety, connectivity, turn-around times for testing and result delivery.
METHODS METHODS
The MBS-Lab was deployed in Senegal in October 2017 for a six-month field assessment under various ecological conditions and was mobilised during the dengue outbreaks in 2017 and 2018.
RESULTS RESULTS
The MBS-Lab can be considered an off-grid solution that addresses field challenges with regard to working conditions, mobility, deployment, environment and personnel safety. Blood (
CONCLUSION CONCLUSIONS
The MBS-Lab is an innovative solution for outbreak response, even in remote areas. The study demonstrated successful local ownership and community engagement. The MBS-Lab can also be considered an open mobile healthcare platform that offers various opportunities for field-deployable, point-of-care technologies for surveillance programmes.

Identifiants

pubmed: 32934915
doi: 10.4102/ajlm.v9i2.1041
pii: AJLM-9-1041
pmc: PMC7479379
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1041

Informations de copyright

© 2020. The Authors.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Cheikh Fall (C)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Aurélie Cappuyns (A)

Praesens Foundation, Brussels, Belgium.

Oumar Faye (O)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Steven Pauwels (S)

Praesens Foundation, Brussels, Belgium.

Gamou Fall (G)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Ndongo Dia (N)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Moussa M Diagne (MM)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Cheikh T Diagne (CT)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Makhtar Niang (M)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Alassane Mbengue (A)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Martin Faye (M)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Idrissa Dieng (I)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Babacar Gningue (B)

Quality Department, Institut Pasteur de Dakar, Dakar, Senegal.

Abdoulaye Bousso (A)

Senegalese Health Emergency Operation Center, Ministry of Health, Dakar, Senegal.

Ousmane Faye (O)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Rudi Pauwels (R)

Praesens Foundation, Brussels, Belgium.

Amadou A Sall (AA)

Department of Virology, Institut Pasteur de Dakar, Dakar, Senegal.

Classifications MeSH