Visual Input into the Drosophila melanogaster Mushroom Body.
Drosophila
Kenyon cells
multisensory integration
mushroom body
visual input
Journal
Cell reports
ISSN: 2211-1247
Titre abrégé: Cell Rep
Pays: United States
ID NLM: 101573691
Informations de publication
Date de publication:
15 09 2020
15 09 2020
Historique:
received:
22
04
2020
revised:
09
07
2020
accepted:
20
08
2020
entrez:
16
9
2020
pubmed:
17
9
2020
medline:
5
5
2021
Statut:
ppublish
Résumé
The patterns of neuronal connectivity underlying multisensory integration, a fundamental property of many brains, remain poorly characterized. The Drosophila melanogaster mushroom body-an associative center-is an ideal system to investigate how different sensory channels converge in higher order brain centers. The neurons connecting the mushroom body to the olfactory system have been described in great detail, but input from other sensory systems remains poorly defined. Here, we use a range of anatomical and genetic techniques to identify two types of input neuron that connect visual processing centers-the lobula and the posterior lateral protocerebrum-to the dorsal accessory calyx of the mushroom body. Together with previous work that described a pathway conveying visual information from the medulla to the ventral accessory calyx of the mushroom body, our study defines a second, parallel pathway that is anatomically poised to convey information from the visual system to the dorsal accessory calyx.
Identifiants
pubmed: 32937130
pii: S2211-1247(20)31127-X
doi: 10.1016/j.celrep.2020.108138
pmc: PMC8252886
mid: NIHMS1629506
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
108138Subventions
Organisme : NINDS NIH HHS
ID : R01 NS106018
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS107970
Pays : United States
Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Interests The authors declare no competing interests.
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