Single-use lidocaine hydrochloride 5 per cent w/v and phenylephrine hydrochloride 0.5 per cent w/v topical spray; can it now be employed as a multi-use atomiser?

Anesthetics, Local Cross Infection Drug Contamination Endoscopy Lidocaine Phenylephrine

Journal

The Journal of laryngology and otology
ISSN: 1748-5460
Titre abrégé: J Laryngol Otol
Pays: England
ID NLM: 8706896

Informations de publication

Date de publication:
17 Sep 2020
Historique:
entrez: 17 9 2020
pubmed: 18 9 2020
medline: 18 9 2020
Statut: aheadofprint

Résumé

This study investigated the risk of contamination of lidocaine hydrochloride 5 per cent w/v and phenylephrine hydrochloride 0.5 per cent w/v topical solution after modification of the application technique. This paper reports a prospective basic sciences study involving 22 study samples and 1 control sample of the lidocaine hydrochloride and phenylephrine hydrochloride topical anaesthetic spray. The samples were assessed for microbiological contamination after a single use on patients using a modified application technique. The modification involves keeping the nozzle (actuator) pressed down whilst withdrawing the spray to at least 30 cm (1 ft) from the patient, before releasing the nozzle (actuator) and subsequently reapplying the spray. Three of the 23 samples confirmed bacterial growth in the bottle contents, but there was no growth in any of the samples from the pump. These bacteria are considered to be contaminants. There is a potential to use the lidocaine hydrochloride 5 per cent w/v and phenylephrine hydrochloride 0.5 per cent w/v topical solution as a multi-use spray by changing the actuator between patients. This would have significant beneficial cost implications without the attendant infection control risk.

Identifiants

pubmed: 32940198
doi: 10.1017/S0022215120001917
pii: S0022215120001917
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-4

Auteurs

M Jog (M)

Department of Otolaryngology, University Hospital Southampton NHS Foundation Trust, UK.

I Zudovaite (I)

Department of Microbiology, University Hospital Southampton NHS Foundation Trust and Microbiology and Innovation Research Unit, UK.

M O'Dwyer (M)

Department of Microbiology, University Hospital Southampton NHS Foundation Trust and Microbiology and Innovation Research Unit, UK.

K Saeed (K)

Department of Microbiology, University Hospital Southampton NHS Foundation Trust and Microbiology and Innovation Research Unit, UK.
School of Medicine, University of Southampton, UK.

T Singh (T)

Department of Otolaryngology, University Hospital Southampton NHS Foundation Trust, UK.

Classifications MeSH