Delayed orthostatic hypotension.

Autonomic Delayed orthostatic hypotension Synucleinopathy

Journal

Autonomic neuroscience : basic & clinical
ISSN: 1872-7484
Titre abrégé: Auton Neurosci
Pays: Netherlands
ID NLM: 100909359

Informations de publication

Date de publication:
12 2020
Historique:
received: 05 08 2020
revised: 24 08 2020
accepted: 02 09 2020
pubmed: 18 9 2020
medline: 6 10 2021
entrez: 17 9 2020
Statut: ppublish

Résumé

Delayed orthostatic hypotension is a fall in blood pressure beyond 3 min of standing or upright tilt table testing. The prevalence, clinical features and pathophysiology are reviewed. To date, there is little data to support a standardized or recommended treatment. However, the 10-year mortality rates of individuals with delayed orthostatic hypotension are approximately 50%. Despite the fact that delayed orthostatic hypotension carries the same symptoms, risks and high mortality rate as classical orthostatic hypotension, but is under-recognized. The frequency with which delayed orthostatic hypotension develops into classical orthostatic hypotension, the high associated mortality rates and risk of development of the neurodegenerative disorders classified as alpha-synucleinopathies underscores the need for further study of this condition.

Identifiants

pubmed: 32942225
pii: S1566-0702(20)30158-2
doi: 10.1016/j.autneu.2020.102724
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102724

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Christopher H Gibbons (CH)

Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: cgibbons@bidmc.harvard.edu.

Roy Freeman (R)

Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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Classifications MeSH