Locally advanced gallbladder cancer: a review of the criteria and role of imaging.


Journal

Abdominal radiology (New York)
ISSN: 2366-0058
Titre abrégé: Abdom Radiol (NY)
Pays: United States
ID NLM: 101674571

Informations de publication

Date de publication:
03 2021
Historique:
received: 10 07 2020
accepted: 03 09 2020
revised: 26 08 2020
pubmed: 19 9 2020
medline: 22 6 2021
entrez: 18 9 2020
Statut: ppublish

Résumé

Gallbladder carcinoma (GBC) is among one of the gastrointestinal malignancies with extremely dismal prognosis. This is due to the advanced stage at presentation. Majority of the patients with GBC are not considered candidates for surgery because of the locally advanced disease or metastases. However, with the accumulating evidence regarding the role of neoadjuvant chemotherapy, there is a need to correctly identify a subset of patients with locally advanced GBC who will benefit maximally from neoadjuvant chemotherapy and will be successfully downstaged to receive curative (R0) surgery. In this context, there is a lack of consensus and different groups have resorted to criteria for locally advanced disease eligible for neoadjuvant chemotherapy based on personal or institutional experiences. Imaging plays a critical role in the evaluation of patients with GBC as it helps stratify patients into resectable and unresectable. Imaging also has the potential to identify patients with locally advanced GBC and hence facilitate neoadjuvant chemotherapy and improve outcomes. In this review, we evaluate the various criteria for locally advanced GBC and the role of imaging in this scenario.

Identifiants

pubmed: 32945922
doi: 10.1007/s00261-020-02756-4
pii: 10.1007/s00261-020-02756-4
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

998-1007

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Auteurs

Pankaj Gupta (P)

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. Pankajgupta959@gmail.com.

Kesha Meghashyam (K)

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Yashi Marodia (Y)

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Vikas Gupta (V)

Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Rajender Basher (R)

Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Chandan Krushna Das (CK)

Department of Radiotherapy, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Thakur Deen Yadav (TD)

Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Santhosh Irrinki (S)

Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Ritambhra Nada (R)

Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

Usha Dutta (U)

Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

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