Effect of Statin Use on the Clinical Manifestations, Laboratory Test Results and Outcome of Lyme Neuroborreliosis.
Bannwarth’s syndrome
Lyme neuroborrelisis
course
outcome
statin
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
16 Sep 2020
16 Sep 2020
Historique:
received:
03
07
2020
revised:
26
08
2020
accepted:
14
09
2020
entrez:
19
9
2020
pubmed:
20
9
2020
medline:
20
9
2020
Statut:
epublish
Résumé
Statins have anti-inflammatory and potentially antimicrobial activity, but whether they have a beneficial effect on the course of infectious diseases is controversial. In this study, we assessed the impact of pre-existing statin use on the course and outcome of Lyme neuroborreliosis manifested as meningoradiculitis (Bannwarth's syndrome). One hundred and twenty three consecutive patients with Bannwarth's syndrome, of whom 18 (14.6%) were being treated with statins, were included in the study. To assess the influence of statin use on the course and outcome of the disease, univariate and multivariable analyses were performed. No statistically significant association was found between statin pre-treatment and the clinical manifestations, laboratory test results, and outcome of Bannwarth's syndrome. In conclusion, pre-existing use of statins did not significantly impact either the clinical presentation or the outcome of Bannwarth's syndrome.
Identifiants
pubmed: 32948002
pii: jcm9092995
doi: 10.3390/jcm9092995
pmc: PMC7563736
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Javna Agencija za Raziskovalno Dejavnost RS
ID : P3-0296
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