In-house rapid colorimetric method for detection of ceftazidime/avibactam resistance in carbapenem resistant Enterobacterales.
ASAT test
categorical agreement
ceftazidime/avibactam
ceftazidime/avibactam-resistance
rapid test
Journal
Journal of chemotherapy (Florence, Italy)
ISSN: 1973-9478
Titre abrégé: J Chemother
Pays: England
ID NLM: 8907348
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
pubmed:
20
9
2020
medline:
27
10
2021
entrez:
19
9
2020
Statut:
ppublish
Résumé
A rapid colorimetric method, the Andrade screening antimicrobial test, was compared with the E-test method to detect ceftazidime/avibactam (CZA) resistance in carbapenem resistant Enterobacterales clinical isolates. A 106 non-duplicated isolates (86 susceptible and 20 resistant to CZA) were chosen for validation. The sensitivity and specificity were 100%. This method investigates CZA resistance regardless of the resistance mechanism involved. It represents an economical and easy technique that can be applied to routine microbiology laboratories. It allows the detection of CZA resistance at 3 hours of incubation and consequently, the early implementation of accurate therapeutic interventions.
Identifiants
pubmed: 32948107
doi: 10.1080/1120009X.2020.1819703
doi:
Substances chimiques
Anti-Bacterial Agents
0
Azabicyclo Compounds
0
Carbapenems
0
Drug Combinations
0
avibactam, ceftazidime drug combination
0
Ceftazidime
9M416Z9QNR
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM