Multi-omics Approaches To Decipher the Impact of Diet and Host Physiology on the Mammalian Gut Microbiome.
diet
mammals
metagenomics
metatranscriptomics
microbiota
physiology
Journal
Applied and environmental microbiology
ISSN: 1098-5336
Titre abrégé: Appl Environ Microbiol
Pays: United States
ID NLM: 7605801
Informations de publication
Date de publication:
10 11 2020
10 11 2020
Historique:
received:
30
07
2020
accepted:
11
09
2020
pubmed:
20
9
2020
medline:
2
12
2020
entrez:
19
9
2020
Statut:
epublish
Résumé
In recent years, various studies have demonstrated that the gut microbiota influences host metabolism. However, these studies were focused primarily on a single or a limited range of host species, thus preventing a full exploration of possible taxonomic and functional adaptations by gut microbiota members as a result of host-microbe coevolution events. In the current study, the microbial taxonomic profiles of 250 fecal samples, corresponding to 77 host species that cover the mammalian branch of the tree of life, were reconstructed by 16S rRNA gene-based sequence analysis. Moreover, shotgun metagenomics was employed to investigate the metabolic potential of the fecal microbiomes of 24 mammals, and subsequent statistical analyses were performed to assess the impact of host diet and corresponding physiology of the digestive system on gut microbiota composition and functionality. Functional data were confirmed and extended through metatranscriptome assessment of gut microbial populations of eight animals, thus providing insights into the transcriptional response of gut microbiota to specific dietary lifestyles. Therefore, the analyses performed in this study support the notion that the metabolic features of the mammalian gut microbiota have adapted to maximize energy extraction from the host's diet.
Identifiants
pubmed: 32948523
pii: AEM.01864-20
doi: 10.1128/AEM.01864-20
pmc: PMC7657629
pii:
doi:
Substances chimiques
RNA, Bacterial
0
RNA, Ribosomal, 16S
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2020 American Society for Microbiology.
Références
J Environ Health Sci Eng. 2013 May 24;11(1):3
pubmed: 24499534
PLoS Biol. 2016 Nov 18;14(11):e2000225
pubmed: 27861590
Microbiome. 2017 May 15;5(1):54
pubmed: 28506279
Science. 2011 May 20;332(6032):970-4
pubmed: 21596990
ISME J. 2019 Mar;13(3):576-587
pubmed: 29995839
Nucleic Acids Res. 2012 Jan;40(Database issue):D742-53
pubmed: 22102576
Nature. 2012 Sep 13;489(7415):242-9
pubmed: 22972297
Nat Methods. 2010 May;7(5):335-6
pubmed: 20383131
Nat Rev Immunol. 2009 May;9(5):313-23
pubmed: 19343057
Ecol Lett. 2014 Oct;17(10):1238-46
pubmed: 25040855
FEMS Microbiol Ecol. 2019 Sep 1;95(9):
pubmed: 31344227
Cell Host Microbe. 2015 Jan 14;17(1):72-84
pubmed: 25532804
Bioinformatics. 2009 Jul 15;25(14):1754-60
pubmed: 19451168
Environ Technol. 2008 May;29(5):559-69
pubmed: 18661740
Int Rev Cytol. 1997;174:195-291
pubmed: 9161008
Nat Commun. 2019 May 16;10(1):2200
pubmed: 31097702
Nat Rev Microbiol. 2008 Oct;6(10):776-88
pubmed: 18794915
Science. 2018 Sep 21;361(6408):
pubmed: 30237322
Science. 2008 Jun 20;320(5883):1647-51
pubmed: 18497261
Eur Heart J. 2019 Feb 14;40(7):583-594
pubmed: 30535398
Nat Methods. 2016 Jul;13(7):581-3
pubmed: 27214047
AMB Express. 2018 Jan 04;8(1):1
pubmed: 29302756
J Plant Res. 2016 Sep;129(5):781-792
pubmed: 27220955
Nature. 2014 Jan 23;505(7484):559-63
pubmed: 24336217
Microbiome. 2018 Aug 20;6(1):145
pubmed: 30126456
Trends Cell Biol. 1996 Nov;6(11):411-4
pubmed: 15157509
Mol Ecol. 2018 Apr;27(8):1884-1897
pubmed: 29290090
mBio. 2020 Jan 7;11(1):
pubmed: 31911491
Infect Immun. 2008 Jun;76(6):2531-40
pubmed: 18347038
Int Microbiol. 2019 Dec;22(4):429-435
pubmed: 30875036
Curr Biol. 2019 Jun 3;29(11):R538-R544
pubmed: 31163167
Cell. 2014 Nov 6;159(4):789-99
pubmed: 25417156
Nucleic Acids Res. 2013 Jan;41(Database issue):D590-6
pubmed: 23193283
Mol Ecol. 2014 Mar;23(6):1268-83
pubmed: 24304129
Nat Commun. 2017 Feb 23;8:14319
pubmed: 28230052
mBio. 2018 Sep 11;9(5):
pubmed: 30206171
Science. 2001 May 11;292(5519):1119-22
pubmed: 11352069
ISME J. 2017 Dec;11(12):2834-2847
pubmed: 28837128
Genome Biol. 2015 Sep 22;16:203
pubmed: 26395444
ISME J. 2015 Mar 17;9(4):832-43
pubmed: 25343515
Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16431-5
pubmed: 25368157
Annu Rev Genet. 2017 Nov 27;51:413-433
pubmed: 28934590
Environ Sci Pollut Res Int. 2002;Spec No 1:27-33
pubmed: 12638745
Microbiology (Reading). 2004 Jul;150(Pt 7):2029-2035
pubmed: 15256547
Appl Environ Microbiol. 2005 Dec;71(12):8228-35
pubmed: 16332807
Microbiome. 2018 May 17;6(1):90
pubmed: 29773078
Bioinformatics. 2012 Jan 1;28(1):125-6
pubmed: 22039206
Curr Biol. 2006 Oct 24;16(20):R866-71
pubmed: 17055966
Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3229-36
pubmed: 23391737
J Microbiol. 2018 Mar;56(3):199-208
pubmed: 29492877
PLoS One. 2013 Jul 15;8(7):e68739
pubmed: 23869230
Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3047-52
pubmed: 21282636
Sci Rep. 2015 Oct 28;5:15782
pubmed: 26506949