Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases.
Journal
Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
03
04
2020
accepted:
28
07
2020
entrez:
19
9
2020
pubmed:
20
9
2020
medline:
14
4
2022
Statut:
epublish
Résumé
Cellular cross-talk between ubiquitination and other posttranslational modifications contributes to the regulation of numerous processes. One example is ADP-ribosylation of the carboxyl terminus of ubiquitin by the E3 DTX3L/ADP-ribosyltransferase PARP9 heterodimer, but the mechanism remains elusive. Here, we show that independently of PARP9, the conserved carboxyl-terminal RING and DTC (Deltex carboxyl-terminal) domains of DTX3L and other human Deltex proteins (DTX1 to DTX4) catalyze ADP-ribosylation of ubiquitin's Gly
Identifiants
pubmed: 32948590
pii: 6/38/eabc0418
doi: 10.1126/sciadv.abc0418
pmc: PMC7500938
pii:
doi:
Substances chimiques
Ubiquitin
0
NAD
0U46U6E8UK
Ubiquitin-Protein Ligases
EC 2.3.2.27
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Cancer Research UK
ID : 29256
Pays : United Kingdom
Organisme : Cancer Research UK
ID : A23278
Pays : United Kingdom
Informations de copyright
Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).
Références
Acta Crystallogr D Biol Crystallogr. 1994 Sep 1;50(Pt 5):760-3
pubmed: 15299374
Nat Rev Mol Cell Biol. 2012 Jun 20;13(7):411-24
pubmed: 22713970
Cell. 2011 Dec 9;147(6):1324-39
pubmed: 22153076
Acta Crystallogr D Biol Crystallogr. 2005 Apr;61(Pt 4):449-57
pubmed: 15805600
Acta Crystallogr D Biol Crystallogr. 2000 Aug;56(Pt 8):965-72
pubmed: 10944333
J Synchrotron Radiat. 2004 Jan 1;11(Pt 1):56-9
pubmed: 14646134
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501
pubmed: 20383002
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):213-21
pubmed: 20124702
Mol Cell. 2017 Oct 19;68(2):456-470.e10
pubmed: 29053960
Structure. 2006 Aug;14(8):1293-302
pubmed: 16905103
Nat Struct Mol Biol. 2007 Oct;14(10):941-8
pubmed: 17873885
Bioinformatics. 2015 Apr 15;31(8):1325-7
pubmed: 25505092
Nat Cell Biol. 2011 May;13(5):623-9
pubmed: 21478859
Mol Cell. 2015 Jun 18;58(6):911-24
pubmed: 26091340
Nat Struct Mol Biol. 2012 Sep;19(9):876-83
pubmed: 22902369
Nat Chem Biol. 2018 Feb 14;14(3):236-243
pubmed: 29443986
EMBO Rep. 2015 Sep;16(9):1071-83
pubmed: 26268526
EMBO J. 2005 Jun 1;24(11):1911-20
pubmed: 15902274
J Mol Biol. 2009 Mar 6;386(4):1011-23
pubmed: 19211026
Acta Crystallogr D Biol Crystallogr. 2010 Jan;66(Pt 1):12-21
pubmed: 20057044
Methods Enzymol. 2005;399:21-36
pubmed: 16338346
Acta Crystallogr D Biol Crystallogr. 2002 Oct;58(Pt 10 Pt 2):1772-9
pubmed: 12351820
Nat Struct Mol Biol. 2013 Aug;20(8):982-986
pubmed: 23851457
Cell. 2016 Dec 1;167(6):1636-1649.e13
pubmed: 27912065
Nat Commun. 2016 Sep 30;7:12917
pubmed: 27686526
Mol Cell. 2013 Oct 24;52(2):272-85
pubmed: 24055347
FEBS J. 2013 Aug;280(15):3491-507
pubmed: 23711178
Proteins. 2012 May;80(5):1495-9
pubmed: 22411408
Structure. 2013 May 7;21(5):727-40
pubmed: 23562397
Nat Rev Mol Cell Biol. 2016 Oct;17(10):626-42
pubmed: 27485899
Anal Biochem. 2011 Nov 1;418(1):102-10
pubmed: 21771579
Methods Mol Biol. 2011;780:209-26
pubmed: 21870263
Nat Methods. 2011 Jul 10;8(8):691-6
pubmed: 21743460
Annu Rev Biochem. 2017 Jun 20;86:159-192
pubmed: 28498721
Biochim Biophys Acta. 2004 Nov 29;1695(1-3):189-207
pubmed: 15571815
Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2228-33
pubmed: 21266548
Annu Rev Biophys Biomol Struct. 2007;36:131-50
pubmed: 17477837
IUCrJ. 2015 Feb 26;2(Pt 2):207-17
pubmed: 25866658
Annu Rev Biochem. 2009;78:399-434
pubmed: 19489725
Cell. 2013 Jun 6;153(6):1312-26
pubmed: 23746843
Mol Cell Biol. 2005 Feb;25(4):1367-78
pubmed: 15684388
Methods Enzymol. 2015;561:171-96
pubmed: 26358905
Cell. 2013 Jul 3;154(1):169-84
pubmed: 23827681
Mol Cell. 2020 May 21;78(4):641-652.e9
pubmed: 32330457
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):293-302
pubmed: 21460447
Mol Cell. 2017 May 18;66(4):503-516.e5
pubmed: 28525742
Mol Cell. 2015 Apr 16;58(2):297-310
pubmed: 25801170
Mol Cell. 2011 Oct 7;44(1):147-59
pubmed: 21981925
Mol Cell. 2012 Sep 28;47(6):933-42
pubmed: 22885007
J Cell Biol. 2004 Aug 16;166(4):487-92
pubmed: 15314065
J Biol Chem. 2005 Oct 7;280(40):33756-65
pubmed: 16061477
Nature. 2012 Sep 6;489(7414):115-20
pubmed: 22842904
Nat Struct Mol Biol. 2010 Jun;17(6):666-72
pubmed: 20495563
Mol Cell. 2007 Dec 14;28(5):730-8
pubmed: 18082598
Nat Med. 2000 Oct;6(10):1073-81
pubmed: 11017125
Nat Struct Mol Biol. 2017 Jul;24(7):578-587
pubmed: 28553961
J Biol Chem. 2003 Jun 13;278(24):21930-7
pubmed: 12670957
Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14103-8
pubmed: 21825151
Acta Crystallogr D Struct Biol. 2018 Feb 1;74(Pt 2):85-97
pubmed: 29533234
J Cell Biol. 2019 Jun 3;218(6):1776-1786
pubmed: 31000580
Acta Crystallogr D Biol Crystallogr. 2009 May;65(Pt 5):510-2
pubmed: 19390156
Trends Biochem Sci. 2010 Apr;35(4):208-19
pubmed: 20106667
Nat Immunol. 2015 Dec;16(12):1215-27
pubmed: 26479788
Mol Cell. 2009 Oct 9;36(1):110-20
pubmed: 19818714
Nature. 2016 May 5;533(7601):120-4
pubmed: 27049943
Nat Struct Biol. 1999 May;6(5):458-63
pubmed: 10331874
Nat Struct Mol Biol. 2012 Jan 22;19(2):184-92
pubmed: 22266821