A Case Report of Oculoglandular Tularemia-Chasing Zebras Among Potential Diagnoses.


Journal

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
ISSN: 1531-5053
Titre abrégé: J Oral Maxillofac Surg
Pays: United States
ID NLM: 8206428

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 03 07 2020
revised: 18 08 2020
accepted: 18 08 2020
pubmed: 20 9 2020
medline: 5 3 2021
entrez: 19 9 2020
Statut: ppublish

Résumé

A 60-year-old man was admitted to a university hospital complaining of progressive orbital cellulitis and lymph-node swelling. Empiric treatment with sulbactam/ampicillin failed. The patient's cervical lymph nodes were removed and histologically examined. Based on the pathological results, acute tuberculosis was suspected but could not be confirmed by further analyses. During an extended screening of agents relevant for differential diagnosis, tularemia was diagnosed serologically and by means of a polymerase chain reaction test, which identified the bacterial subspecies Francisella tularensis holarctica. Treatment with ciprofloxacin was administered and later changed to doxycycline due to side effects. The patient made a full recovery without any sequelae. Clinical diagnosis of tularemia is often delayed due to its nonspecific symptoms, which can be caused by several infectious and noninfectious diseases. We try to give an overview of potential differential diagnoses and corresponding diagnostic techniques that can shorten the path to suitable treatment.

Identifiants

pubmed: 32949503
pii: S0278-2391(20)31083-1
doi: 10.1016/j.joms.2020.08.018
pii:
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

629-636

Informations de copyright

Copyright © 2020 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Auteurs

Tobias Kreutzmann (T)

Resident, Department of Oral, Craniomaxillofacial and Facial Plastic Surgery, Leipzig University Hospital, Leipzig, Germany. Electronic address: tobias.kreutzmann@medizin.uni-leipzig.de.

Annika Schönfeld (A)

Resident, Department of Oral, Craniomaxillofacial and Facial Plastic Surgery, Leipzig University Hospital, Leipzig, Germany.

Sabine Zange (S)

Specialist, Bundeswehr Institute of Microbiology, Munich, Germany.

Bernd Lethaus (B)

Head of Department, Department of Oral, Craniomaxillofacial and Facial Plastic Surgery, Leipzig University Hospital, Leipzig, Germany.

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Classifications MeSH