Iron Deficiency Anemia in Pregnancy: Novel Approaches for an Old Problem.
Anemia, Iron-Deficiency
Iron
Pregnancy
Pregnancy Outcome
Prenatal Care
Journal
Oman medical journal
ISSN: 1999-768X
Titre abrégé: Oman Med J
Pays: Oman
ID NLM: 101526350
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
10
02
2019
accepted:
27
03
2019
entrez:
21
9
2020
pubmed:
22
9
2020
medline:
22
9
2020
Statut:
epublish
Résumé
Iron needs increase exponentially during pregnancy to meet the increased demands of the fetoplacental unit, to expand maternal erythrocyte mass, and to compensate for iron loss at delivery. In more than 80% of countries in the world, the prevalence of anemia in pregnancy is > 20% and could be considered a major public health problem. The global prevalence of anemia in pregnancy is estimated to be approximately 41.8%. Undiagnosed and untreated iron deficiency anemia (IDA) can have a great impact on maternal and fetal health. Indeed, chronic iron deficiency can affect the general wellbeing of the mother and leads to fatigue and reduced working capacity. Given the significant adverse impact on maternal-fetal outcomes, early recognition and treatment of this clinical condition is fundamental. Therefore, the laboratory assays are recommended from the first trimester to evaluate the iron status. Oral iron supplementation is the first line of treatment in cases of mild anemia. However, considering the numerous gastrointestinal side effects that often lead to poor compliance, other therapeutic strategies should be evaluated. This review aims to provide an overview of the current evidence about the management of IDA in pregnancy and available treatment options.
Identifiants
pubmed: 32953141
doi: 10.5001/omj.2020.108
pii: OMJ-35-05-1900044
pmc: PMC7477519
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e166Informations de copyright
The OMJ is Published Bimonthly and Copyrighted 2020 by the OMSB.
Références
Nutr Rev. 2011 Nov;69 Suppl 1:S23-9
pubmed: 22043878
Biomed Res Int. 2017;2017:6073167
pubmed: 28466013
Int J Gynaecol Obstet. 2007 Aug;98(2):124-8
pubmed: 17585914
Cochrane Database Syst Rev. 2015 Jul 22;(7):CD004736
pubmed: 26198451
Aust N Z J Obstet Gynaecol. 2018 Feb;58(1):22-39
pubmed: 28921558
Lancet Haematol. 2017 Nov;4(11):e524-e533
pubmed: 29032957
Nutr Hosp. 2014 Jun 01;29(6):1240-9
pubmed: 24972460
Ann Hematol. 2011 Apr;90(4):369-77
pubmed: 21221586
Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):57-66
pubmed: 27913463
Lancet. 2016 Feb 27;387(10021):907-16
pubmed: 26314490
Public Health Nutr. 2009 Apr;12(4):444-54
pubmed: 18498676
Best Pract Res Clin Obstet Gynaecol. 2012 Feb;26(1):3-24
pubmed: 22138002
Hypertension. 2009 Jun;53(6):944-51
pubmed: 19433776
Am J Clin Nutr. 2005 May;81(5):1218S-1222S
pubmed: 15883455
J Matern Fetal Neonatal Med. 2017 May;30(10):1249-1253
pubmed: 27442264
J Matern Fetal Neonatal Med. 2011 Nov;24(11):1347-52
pubmed: 21859366
Am J Clin Nutr. 2017 Dec;106(Suppl 6):1655S-1662S
pubmed: 29070543
Nutr Rev. 2013 Jan;71(1):35-51
pubmed: 23282250
Turk J Obstet Gynecol. 2015 Sep;12(3):173-181
pubmed: 28913064
Arzneimittelforschung. 2007;57(6A):439-52
pubmed: 17691594
Eur J Clin Nutr. 2009 Feb;63(2):183-90
pubmed: 17928802
Nutrients. 2016 Nov 29;8(12):
pubmed: 27916823
Int J Gynaecol Obstet. 2018 Jun;141(3):315-320
pubmed: 29498039
Arch Gynecol Obstet. 2018 Apr;297(4):823-835
pubmed: 29236171
Minerva Ginecol. 2017 Dec;69(6):618-630
pubmed: 29082726
Diabet Med. 2005 Nov;22(11):1536-41
pubmed: 16241919
Eur Rev Med Pharmacol Sci. 2017 Sep;21(18):4243-4251
pubmed: 29028072
Nephrol Dial Transplant. 2015 Apr;30(4):645-52
pubmed: 25395392
Nutr Rev. 2013 Feb;71(2):118-32
pubmed: 23356639
J Pregnancy. 2012;2012:630519
pubmed: 22792466
Semin Hematol. 2015 Oct;52(4):339-47
pubmed: 26404445
J Matern Fetal Neonatal Med. 2018 Nov;31(22):3033-3038
pubmed: 28760050
Cochrane Database Syst Rev. 2016 Apr 18;4:CD009747
pubmed: 27087396
J Matern Fetal Neonatal Med. 2018 Mar;31(6):817-821
pubmed: 28282763
J Matern Fetal Neonatal Med. 2017 Aug;30(15):1787-1792
pubmed: 27588568
Aust N Z J Obstet Gynaecol. 2018 Apr;58(2):163-169
pubmed: 28608544
Gynecol Obstet Invest. 1993;35(3):162-5
pubmed: 8505008
Reprod Health. 2018 Jun 22;15(Suppl 1):93
pubmed: 29945643
Obstet Gynecol. 2012 Jun;119(6):1308-17
pubmed: 22617615
Am J Clin Nutr. 2017 Dec;106(Suppl 6):1567S-1574S
pubmed: 29070542
Eur J Nutr. 2015 Dec;54(8):1345-52
pubmed: 25526967
Int J Endocrinol. 2017;2017:5846286
pubmed: 28243254
Indian J Med Res. 2013;138:78-82
pubmed: 24056559
Arch Gynecol Obstet. 2017 Dec;296(6):1229-1234
pubmed: 28940095
Expert Opin Drug Metab Toxicol. 2018 Sep;14(9):887-889
pubmed: 30058386
Horm Mol Biol Clin Investig. 2016 Jan;25(1):15-28
pubmed: 26943610
Cochrane Database Syst Rev. 2009 Oct 07;(4):CD001300
pubmed: 19821276
Gut. 2012 Jun;61(6):933-52
pubmed: 22016365
Hematology Am Soc Hematol Educ Program. 2017 Dec 8;2017(1):152-159
pubmed: 29222250
Acta Biochim Pol. 2000;47(3):639-49
pubmed: 11310966
J Perinat Med. 2012 May 13;40(5):469-74
pubmed: 22945271
Am J Clin Nutr. 2005 May;81(5):1246S-1251S
pubmed: 15883459
Am J Obstet Gynecol. 2004 Nov;191(5):1655-60
pubmed: 15547538
Int J Gynaecol Obstet. 2015 Mar;128(3):196-200
pubmed: 25627706
Arch Gynecol Obstet. 2017 Nov;296(5):855-867
pubmed: 28875276
Evid Based Med. 2015 Dec;20(6):208
pubmed: 26442565
Med Hypotheses. 2017 Jun;103:10-20
pubmed: 28571791
Hematol Oncol Clin North Am. 2016 Apr;30(2):247-308
pubmed: 27040955
Expert Opin Drug Metab Toxicol. 2017 Jun;13(6):593-596
pubmed: 28537213
Arch Gynecol Obstet. 2017 Apr;295(4):867-872
pubmed: 28243732
J Womens Health (Larchmt). 2012 Dec;21(12):1282-9
pubmed: 23210492
Obstet Gynecol Surv. 2016 Dec;71(12):721-733
pubmed: 28005135
Rev Assoc Med Bras (1992). 2015 Nov-Dec;61(6):519-23
pubmed: 26841161
Arch Ital Urol Androl. 2017 Dec 31;89(4):287-292
pubmed: 29473378
Blood. 2014 Jan 30;123(5):615-24
pubmed: 24297872
Food Nutr Bull. 2007 Dec;28(4 Suppl):S560-71
pubmed: 18297894
N Engl J Med. 2015 May 7;372(19):1832-43
pubmed: 25946282
Br J Hosp Med (Lond). 2016 Oct;77(10):584-588
pubmed: 27723395
Am J Clin Nutr. 2000 Jul;72(1 Suppl):257S-264S
pubmed: 10871591
Biomed Res Int. 2017;2017:6848250
pubmed: 28948169
Am J Clin Nutr. 2013 Dec;98(6):1425-32
pubmed: 24132976
Obstet Gynecol. 2008 Jul;112(1):201-7
pubmed: 18591330
Cochrane Database Syst Rev. 2016 Sep 07;9:CD012048
pubmed: 27602537
Expert Rev Hematol. 2018 Sep;11(9):727-736
pubmed: 30019973
J Matern Fetal Neonatal Med. 2017 Apr;30(8):977-982
pubmed: 27238247
Biomed Res Int. 2016;2016:3617179
pubmed: 27579309