Anterior segment parameters associated with extramuscular manifestations in polymyositis and dermatomyositis.
Scheimpflug imaging
dermatomyositis
dry eye
extramuscular manifestations
polymyositis
Journal
International journal of ophthalmology
ISSN: 2222-3959
Titre abrégé: Int J Ophthalmol
Pays: China
ID NLM: 101553860
Informations de publication
Date de publication:
2020
2020
Historique:
received:
12
09
2019
accepted:
13
05
2020
entrez:
21
9
2020
pubmed:
22
9
2020
medline:
22
9
2020
Statut:
epublish
Résumé
To evaluate detailed anterior segment parameters of patients with idiopathic inflammatory myopathies (IIM), including polymyositis (PM), and dermatomyositis (DM), and to clarify the associations between these data and clinical variables of IIM. Totally 57 PM, 41 DM patients and 62 controls were enrolled in this cross-sectional, observational, case-control study. All study participants underwent Pentacam evaluation. Laboratory investigations consisted of different antibody assays, while extramuscular clinical assessments included Raynaud's phenomenon, dysphagia, interstitial lung disease, arthritis/arthralgia, and weight loss. Objective signs and subjective symptoms of dry eye disease (DED) were also evaluated. All pachymetric parameters [center, apex, thinnest and maximal keratometry (K The results suggest that all IIM patients have thinner corneas compared with those of controls, and decreased corneal parameters are significantly associated with the occurrence of some extramuscular manifestations. In addition, IIM patients tend to develop objective signs of DED.
Identifiants
pubmed: 32953585
doi: 10.18240/ijo.2020.09.17
pii: ijo-13-09-1443
pmc: PMC7459236
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1443-1450Informations de copyright
International Journal of Ophthalmology Press.
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