Rapid In-Process Monitoring of Lentiviral Vector Particles by High-Performance Liquid Chromatography.

Process Analytical Technologies high-performance liquid chromatography lentiviral vector particle quantification ratio transducing units to total particles

Journal

Molecular therapy. Methods & clinical development
ISSN: 2329-0501
Titre abrégé: Mol Ther Methods Clin Dev
Pays: United States
ID NLM: 101624857

Informations de publication

Date de publication:
11 Sep 2020
Historique:
received: 27 03 2020
accepted: 31 07 2020
entrez: 21 9 2020
pubmed: 22 9 2020
medline: 22 9 2020
Statut: epublish

Résumé

Lentiviral vectors (LVs) are a popular gene delivery tool in cell and gene therapy and they are a primary tool for

Identifiants

pubmed: 32953931
doi: 10.1016/j.omtm.2020.08.005
pii: S2329-0501(20)30171-6
pmc: PMC7479275
doi:

Types de publication

Journal Article

Langues

eng

Pagination

803-810

Informations de copyright

Crown Copyright © 2020.

Références

J Chromatogr B Biomed Sci Appl. 2000 Apr 14;740(2):195-202
pubmed: 10821405
J Biotechnol. 2016 Dec 20;240:23-30
pubmed: 27769802
J Chromatogr B Biomed Sci Appl. 2001 May 5;755(1-2):27-36
pubmed: 11393714
Virology. 1997 Mar 31;230(1):125-33
pubmed: 9126268
BMC Biotechnol. 2006 Jul 12;6:34
pubmed: 16836756
Gene Ther. 2005 Oct;12 Suppl 1:S36-50
pubmed: 16231054
Hum Gene Ther. 2003 Apr 10;14(6):497-507
pubmed: 12718761
Biotechniques. 2001 Sep;31(3):520, 522, 524, passim
pubmed: 11570495
J Virol Methods. 1987 Jun;16(3):209-16
pubmed: 3654898
Vaccine. 2015 Jan 1;33(1):78-84
pubmed: 25448111
J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jan 1;879(1):61-8
pubmed: 21123120
J Pharm Biomed Anal. 2008 Nov 4;48(3):598-605
pubmed: 18632239
Mol Biotechnol. 2015 Feb;57(2):195-200
pubmed: 25370825
Gene Ther. 2002 Sep;9(17):1155-62
pubmed: 12170379
Infect Genet Evol. 2017 Sep;53:146-154
pubmed: 28546080
Hum Gene Ther Methods. 2017 Dec;28(6):330-339
pubmed: 28826344
J Immunol Methods. 2008 Sep 30;338(1-2):21-30
pubmed: 18675270
Vaccine. 2009 Feb 25;27(9):1468-77
pubmed: 19110022
Virology. 2010 Nov 25;407(2):281-8
pubmed: 20850162
J Virol. 1999 Apr;73(4):2886-92
pubmed: 10074136
Virology. 1997 Mar 31;230(1):134-44
pubmed: 9126269
J Chromatogr B Biomed Sci Appl. 2001 Sep 25;761(2):187-94
pubmed: 11587348
Hum Gene Ther Methods. 2018 Apr;29(2):96-103
pubmed: 29378428
Leukemia. 2018 Jul;32(7):1529-1541
pubmed: 29654266

Auteurs

Julia Transfiguracion (J)

National Research Council, Human Health Therapeutics Research Center, 6100 Royalmount Avenue, Montreal, QC H4P 2R2, Canada.

Michelle Yen Tran (MY)

Viral Vectors and Vaccine Bioprocessing Group, Department of Bioengineering, McGill University, 817 Sherbrooke West #270, Montreal, QC H3A 0C3, Canada.

Stéphane Lanthier (S)

National Research Council, Human Health Therapeutics Research Center, 6100 Royalmount Avenue, Montreal, QC H4P 2R2, Canada.

Sonia Tremblay (S)

National Research Council, Human Health Therapeutics Research Center, 6100 Royalmount Avenue, Montreal, QC H4P 2R2, Canada.

Nathalie Coulombe (N)

National Research Council, Human Health Therapeutics Research Center, 6100 Royalmount Avenue, Montreal, QC H4P 2R2, Canada.

Mauro Acchione (M)

National Research Council, Human Health Therapeutics Research Center, 6100 Royalmount Avenue, Montreal, QC H4P 2R2, Canada.

Amine A Kamen (AA)

National Research Council, Human Health Therapeutics Research Center, 6100 Royalmount Avenue, Montreal, QC H4P 2R2, Canada.
Viral Vectors and Vaccine Bioprocessing Group, Department of Bioengineering, McGill University, 817 Sherbrooke West #270, Montreal, QC H3A 0C3, Canada.

Classifications MeSH