Tactile direction discrimination in humans after stroke.
direction discrimination
somatosensory system
stroke
structural MRI
touch
Journal
Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125
Informations de publication
Date de publication:
2020
2020
Historique:
received:
20
05
2019
revised:
27
04
2020
accepted:
22
05
2020
entrez:
21
9
2020
pubmed:
22
9
2020
medline:
22
9
2020
Statut:
epublish
Résumé
Sensing movements across the skin surface is a complex task for the tactile sensory system, relying on sophisticated cortical processing. Functional MRI has shown that judgements of the direction of tactile stimuli moving across the skin are processed in distributed cortical areas in healthy humans. To further study which brain areas are important for tactile direction discrimination, we performed a lesion study, examining a group of patients with first-time stroke. We measured tactile direction discrimination in 44 patients, bilaterally on the dorsum of the hands and feet, within 2 weeks (acute), and again in 28 patients 3 months after stroke. The 3-month follow-up also included a structural MRI scan for lesion delineation. Fifty-nine healthy participants were examined for normative direction discrimination values. We found abnormal tactile direction discrimination in 29/44 patients in the acute phase, and in 21/28 3 months after stroke. Lesions that included the opercular parietal area 1 of the secondary somatosensory cortex, the dorsolateral prefrontal cortex or the insular cortex were always associated with abnormal tactile direction discrimination, consistent with previous functional MRI results. Abnormal tactile direction discrimination was also present with lesions including white matter and subcortical regions. We have thus delineated cortical, subcortical and white matter areas important for tactile direction discrimination function. The findings also suggest that tactile dysfunction is common following stroke.
Identifiants
pubmed: 32954335
doi: 10.1093/braincomms/fcaa088
pii: fcaa088
pmc: PMC7472910
doi:
Types de publication
Journal Article
Langues
eng
Pagination
fcaa088Informations de copyright
© The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain.
Références
Trans Am Neurol Assoc. 1973;98:118-22
pubmed: 4784916
Cereb Cortex. 1999 Oct-Nov;9(7):662-74
pubmed: 10554989
Front Neurol. 2019 Jan 10;9:1129
pubmed: 30687211
Biomed Res Int. 2013;2013:734326
pubmed: 23936840
Elife. 2019 Dec 24;8:
pubmed: 31872799
Nat Neurosci. 2002 Sep;5(9):900-4
pubmed: 12145636
Nat Neurosci. 2000 Mar;3(3):277-83
pubmed: 10700261
Nat Neurosci. 2014 Sep;17(9):1233-9
pubmed: 25064850
Arch Phys Med Rehabil. 2000 Oct;81(10):1357-63
pubmed: 11030501
Neuron. 2001 Jan;29(1):287-96
pubmed: 11182099
J Neurosci. 2000 Jan 1;20(1):RC51
pubmed: 10627628
J Neurophysiol. 1990 Jun;63(6):1323-32
pubmed: 2358880
PLoS Biol. 2010 Feb 02;8(2):e1000305
pubmed: 20126380
Dev Cogn Neurosci. 2019 Feb;35:94-103
pubmed: 29291986
Clin Rehabil. 2008 Aug;22(8):758-67
pubmed: 18678576
Stroke. 2019 May;50(5):1116-1123
pubmed: 30943883
Brain Res. 2000 Jun 2;866(1-2):178-87
pubmed: 10825493
J Neurosci. 2007 Aug 1;27(31):8261-7
pubmed: 17670972
Brain Res. 1985 Dec;357(3):213-30
pubmed: 3938308
Neurorehabil Neural Repair. 2008 Mar-Apr;22(2):166-72
pubmed: 17687023
J Neurol Neurosurg Psychiatry. 1989 Mar;52(3):395-8
pubmed: 2926427
Clin Neurophysiol. 2003 May;114(5):915-29
pubmed: 12738439
Somatosens Mot Res. 1996;13(2):153-66
pubmed: 8844964
Brain Res. 1998 Oct 12;808(1):120-3
pubmed: 9795181
Cogn Neuropsychol. 2010 May;27(3):245-60
pubmed: 20936548
Nat Neurosci. 2009 May;12(5):547-8
pubmed: 19363489
IEEE Trans Haptics. 2010 Jul-Sep;3(3):177-188
pubmed: 27788072
Neurosci Lett. 2011 Aug 21;501(1):45-9
pubmed: 21741443
Neuropsychologia. 2005;43(3):332-9
pubmed: 15707611
Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5693-E5702
pubmed: 28652360
BMJ Case Rep. 2012 Oct 06;2012:
pubmed: 23045439
Neuropsychology. 2006 May;20(3):259-71
pubmed: 16719619
Brain Res. 2012 Jun 15;1460:78-87
pubmed: 22592076
J Physiol. 1994 Aug 1;478 Pt 3:533-40
pubmed: 7965863
Somatosens Mot Res. 2008 Sep;25(3):149-62
pubmed: 18821280
Neuroimage. 2003 Jul;19(3):1233-9
pubmed: 12880848
J Neurosci. 2006 Nov 29;26(48):12596-601
pubmed: 17135421
Acta Neurol Scand. 2010 May;121(5):302-8
pubmed: 19804478
J Neurol Sci. 1982 Mar;53(3):531-55
pubmed: 6279783
Front Hum Neurosci. 2012 Jul 17;6:195
pubmed: 22822394
Exp Brain Res. 2008 Sep;190(2):117-24
pubmed: 18574581
Somatosens Mot Res. 1996;13(1):73-80
pubmed: 8725651
Brain. 2015 Mar;138(Pt 3):540-8
pubmed: 25541190
Neuroimage. 2012 Mar;60(1):409-18
pubmed: 22245639
Clin Rehabil. 1999 Feb;13(1):48-55
pubmed: 10327097
J Neurophysiol. 2009 Sep;102(3):1623-31
pubmed: 19553476
Neurosci Lett. 2010 Oct 15;483(3):197-200
pubmed: 20708069
J Neurophysiol. 1989 Dec;62(6):1410-36
pubmed: 2600632
Nat Rev Neurosci. 2009 Jan;10(1):59-70
pubmed: 19096369
Muscle Nerve. 2001 Nov;24(11):1496-502
pubmed: 11745952
Cereb Cortex. 2006 Feb;16(2):268-79
pubmed: 15888606
J Neurophysiol. 1992 May;67(5):1105-13
pubmed: 1597700
Sens Processes. 1978 Jun;2(2):71-9
pubmed: 715470
Neuron. 2014 May 21;82(4):737-55
pubmed: 24853935
Muscle Nerve. 1997 Nov;20(11):1414-21
pubmed: 9342158
J Neurophysiol. 2016 Mar;115(3):1703-12
pubmed: 26823511
J Physiol. 2019 Aug;597(16):4357-4371
pubmed: 31342538
Arch Phys Med Rehabil. 1993 Jun;74(6):602-11
pubmed: 8503750
Brain. 2001 May;124(Pt 5):916-27
pubmed: 11335694
J Neurol. 2003 Jul;250(7):850-60
pubmed: 12883929
Neuroimage Clin. 2015 Dec 11;10:257-66
pubmed: 26900565
Nature. 1973 Sep 7;245(5419):41-2
pubmed: 4583128
Exp Brain Res. 2012 Feb;216(4):535-44
pubmed: 22120108
J Neurophysiol. 2013 Oct;110(7):1554-66
pubmed: 23843433
Neuroimage. 2014 May 1;91:300-10
pubmed: 24434679
J Neurophysiol. 2011 Sep;106(3):1125-65
pubmed: 21653723