Stereotactic radiofrequency ablation of a variety of liver masses in children.


Journal

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
ISSN: 1464-5157
Titre abrégé: Int J Hyperthermia
Pays: England
ID NLM: 8508395

Informations de publication

Date de publication:
2020
Historique:
entrez: 21 9 2020
pubmed: 22 9 2020
medline: 25 6 2021
Statut: ppublish

Résumé

Surgical resection is currently the cornerstone of liver tumor treatment in children. In adults radiofrequency ablation (RFA) is an established minimally invasive treatment option for small focal liver tumors. Multiprobe stereotactic RFA (SRFA) with intraoperative image fusion to confirm ablation margins allows treatment for large lesions. We describe our experience with SRFA in children with liver masses. SRFA was performed in 10 patients with a median age of 14 years (range 0.5-17.0 years) suffering from liver adenoma ( The technical success rate was 100%, as was the survival rate. No transient adverse effects higher than grade II (Clavien and Dindo) were encountered after interventions. The median hospital stay was 5 d (range 2-33 d). In two patients who subsequently underwent transplant hepatectomy complete ablation was histologically confirmed. Follow-up imaging studies (median 55 months, range 18-129 months) revealed no local or distant recurrence of disease in any patient. SRFA is an effective minimal-invasive treatment option in pediatric patients with liver tumors of different etiologies.

Sections du résumé

BACKGROUND AND AIMS
Surgical resection is currently the cornerstone of liver tumor treatment in children. In adults radiofrequency ablation (RFA) is an established minimally invasive treatment option for small focal liver tumors. Multiprobe stereotactic RFA (SRFA) with intraoperative image fusion to confirm ablation margins allows treatment for large lesions. We describe our experience with SRFA in children with liver masses.
METHODS
SRFA was performed in 10 patients with a median age of 14 years (range 0.5-17.0 years) suffering from liver adenoma (
RESULTS
The technical success rate was 100%, as was the survival rate. No transient adverse effects higher than grade II (Clavien and Dindo) were encountered after interventions. The median hospital stay was 5 d (range 2-33 d). In two patients who subsequently underwent transplant hepatectomy complete ablation was histologically confirmed. Follow-up imaging studies (median 55 months, range 18-129 months) revealed no local or distant recurrence of disease in any patient.
CONCLUSIONS
SRFA is an effective minimal-invasive treatment option in pediatric patients with liver tumors of different etiologies.

Identifiants

pubmed: 32954876
doi: 10.1080/02656736.2020.1822549
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1074-1081

Auteurs

Benjamin Hetzer (B)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Georg-Friedrich Vogel (GF)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Andreas Entenmann (A)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Michel Heil (M)

Department of Radiology, Interventional Oncology-Microinvasive Therapy (SIP), Medical University of Innsbruck, Innsbruck, Austria.

Peter Schullian (P)

Department of Radiology, Interventional Oncology-Microinvasive Therapy (SIP), Medical University of Innsbruck, Innsbruck, Austria.

Daniel Putzer (D)

Department of Radiology, Interventional Oncology-Microinvasive Therapy (SIP), Medical University of Innsbruck, Innsbruck, Austria.

Bernhard Meister (B)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Roman Crazzolara (R)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Gabriele Kropshofer (G)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Christina Salvador (C)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Simon Straub (S)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Daniela Karall (D)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Christian Niederwanger (C)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Gérard Cortina (G)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Andreas Janecke (A)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Karin Freund-Unsinn (K)

Department of Radiology, Interventional Oncology-Microinvasive Therapy (SIP), Medical University of Innsbruck, Innsbruck, Austria.

Kathrin Maurer (K)

Department of Radiology, Interventional Oncology-Microinvasive Therapy (SIP), Medical University of Innsbruck, Innsbruck, Austria.

Gisela Schweigmann (G)

Department of Radiology, Interventional Oncology-Microinvasive Therapy (SIP), Medical University of Innsbruck, Innsbruck, Austria.

Georg Oberhuber (G)

INNPATH, Institute of Pathology, Tirol Kliniken Innsbruck, Innsbruck, Austria.

Oliver Renz (O)

Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.

Stefan Schneeberger (S)

Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.

Thomas Müller (T)

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Reto Bale (R)

Department of Radiology, Interventional Oncology-Microinvasive Therapy (SIP), Medical University of Innsbruck, Innsbruck, Austria.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH