Fear of Cancer Recurrence in Patients With Localized Renal Cell Carcinoma.


Journal

JCO oncology practice
ISSN: 2688-1535
Titre abrégé: JCO Oncol Pract
Pays: United States
ID NLM: 101758685

Informations de publication

Date de publication:
11 2020
Historique:
pubmed: 22 9 2020
medline: 25 6 2021
entrez: 21 9 2020
Statut: ppublish

Résumé

Patients with cancer commonly report distress and fear of cancer recurrence (FCR) impacting quality of life and clinical outcomes. This study aims to test the association between emotional well-being and clinical characteristics of survivors with localized renal cell carcinoma (RCC). Survivors with localized RCC were invited to participate in this study through social media by the Kidney Cancer Research Alliance. Participants self-reported clinical characteristics, distress (Distress Thermometer), and FCR (Fear of Cancer Recurrence-7). Ordinal regression was used to test the association between emotional well-being and patient characteristics. A total of 412 survivors were included in this analysis. Participants were mostly female (79.4%) and well educated (58.3%), with a median age of 54 years (range, 30-80 years) and median time since diagnosis of 17.5 months. More than one half were diagnosed with stage I disease (56.1%). Most patients (62.3%) had a clear understanding of their diagnosis. A high prevalence of moderate to severe distress (67.0%) and FCR (54.9%) was reported across all survivors of RCC. Higher FCR was associated with female gender, younger age, and lack of understanding of their diagnosis ( Our findings suggest that FCR is a common problem that is persistent after therapy and that certain individuals, including female and younger patients, may be at particular risk of experiencing clinically relevant FCR.

Identifiants

pubmed: 32955409
doi: 10.1200/OP.20.00105
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e1264-e1271

Déclaration de conflit d'intérêts

Conflicts of Interest Statement:The authors have declared that no competing interests exist.

Auteurs

Cristiane Decat Bergerot (CD)

Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA.

Dena Battle (D)

Kidney Cancer Research Alliance, Alexandria, VA.

Errol J Philip (EJ)

University of California, San Francisco, San Francisco, CA.

Paulo Gustavo Bergerot (PG)

Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA.

Pavlos Msaouel (P)

Division of Cancer Medicine, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

Allan 'Ben' Smith (A')

Centre for Oncology Education and Research Translation, Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia.

Adeola Esther Bamgboje (AE)

Centre for Oncology Education and Research Translation, Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia.

Brian Shuch (B)

Ronald Reagan UCLA Medical Center, University of California Los Angeles Medical Center, Los Angeles, CA.

Ithaar H Derweesh (IH)

University of California, San Diego, San Diego, CA.

Eric Jonasch (E)

Division of Cancer Medicine, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

Adam P Stern (AP)

Harvard Medical School, Boston, MA.

Sumanta K Pal (SK)

Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA.

Michael Staehler (M)

Department of Urology, Ludwig-Maximilians University, Munich, Germany.

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Classifications MeSH