High 18F-FDOPA PET Uptake in Primary Central Nervous System Lymphoma.
Journal
Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
pubmed:
22
9
2020
medline:
29
12
2020
entrez:
21
9
2020
Statut:
ppublish
Résumé
We present a 42-year-old woman with primary central nervous system lymphoma (PCNSL) and strong F-FDOPA PET uptake. F-FDOPA PET has high diagnostic accuracy in gliomas and brain metastases. The L-type amino acid transporter 1, targeted by F-FDOPA and C-MET PET, is a cell-type transporter usually upregulated in malignant tumors, including PCNSL. In this line, strong uptake was already shown with C-MET in PCNSL. We report the same findings with F-FDOPA. Consequently, PCNSL is a possible differential neoplastic diagnosis of F-FDOPA uptake among neoplastic lesions.
Identifiants
pubmed: 32956128
doi: 10.1097/RLU.0000000000003303
pii: 00003072-202101000-00054
doi:
Substances chimiques
fluorodopa F 18
2C598205QX
Dihydroxyphenylalanine
63-84-3
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e59-e60Références
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