Capillary Electrophoresis-Mass Spectrometry at Trial by Metabo-Ring: Effective Electrophoretic Mobility for Reproducible and Robust Compound Annotation.
Journal
Analytical chemistry
ISSN: 1520-6882
Titre abrégé: Anal Chem
Pays: United States
ID NLM: 0370536
Informations de publication
Date de publication:
20 10 2020
20 10 2020
Historique:
pubmed:
23
9
2020
medline:
4
3
2021
entrez:
22
9
2020
Statut:
ppublish
Résumé
Capillary zone electrophoresis-mass spectrometry (CE-MS) is a mature analytical tool for the efficient profiling of (highly) polar and ionizable compounds. However, the use of CE-MS in comparison to other separation techniques remains underrepresented in metabolomics, as this analytical approach is still perceived as technically challenging and less reproducible, notably for migration time. The latter is key for a reliable comparison of metabolic profiles and for unknown biomarker identification that is complementary to high resolution MS/MS. In this work, we present the results of a Metabo-ring trial involving 16 CE-MS platforms among 13 different laboratories spanning two continents. The goal was to assess the reproducibility and identification capability of CE-MS by employing effective electrophoretic mobility (μ
Identifiants
pubmed: 32961048
doi: 10.1021/acs.analchem.0c03129
pmc: PMC7581015
doi:
Substances chimiques
Cations
0
Electrolytes
0
Organic Chemicals
0
Types de publication
Clinical Trial
Journal Article
Multicenter Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
14103-14112Subventions
Organisme : NIGMS NIH HHS
ID : R35 GM124755
Pays : United States
Références
Clin Kidney J. 2017 Apr;10(2):192-201
pubmed: 28694965
Elife. 2020 Mar 09;9:
pubmed: 32149608
Electrophoresis. 2020 Mar;41(5-6):360-369
pubmed: 31907937
Ther Drug Monit. 2005 Dec;27(6):747-51
pubmed: 16404815
Analyst. 2017 Aug 21;142(17):3079-3100
pubmed: 28792021
J Sep Sci. 2015 Sep;38(18):3262-3270
pubmed: 26147246
Nucleic Acids Res. 2018 Jan 4;46(D1):D608-D617
pubmed: 29140435
J Pharm Biomed Anal. 2018 Sep 10;159:53-59
pubmed: 29980019
Analyst. 2019 Nov 4;144(22):6595-6608
pubmed: 31608347
Methods Mol Biol. 2020;2084:55-78
pubmed: 31729653
Methods Mol Biol. 2011;708:229-46
pubmed: 21207294
Methods Mol Biol. 2017;1550:339-368
pubmed: 28188540
J Proteome Res. 2003 Sep-Oct;2(5):488-94
pubmed: 14582645
J Vis Exp. 2016 Oct 1;(116):
pubmed: 27768073
J Biol Chem. 2006 Jun 16;281(24):16768-76
pubmed: 16608839
Anal Chem. 2007 Jan 15;79(2):403-15
pubmed: 17222002
Electrophoresis. 2018 Mar;39(5-6):853-861
pubmed: 29124762
J Chromatogr A. 2000 Feb 11;869(1-2):375-84
pubmed: 10720252
J Pharm Biomed Anal. 2018 Nov 30;161:414-424
pubmed: 30216790
Proc Natl Acad Sci U S A. 2015 May 26;112(21):6545-50
pubmed: 25941375
J Pharm Biomed Anal. 2011 Jun 25;55(4):823-31
pubmed: 21376499
Anal Chem. 2008 May 1;80(9):3112-22
pubmed: 18384203
Anal Chem. 2009 Mar 15;81(6):2135-43
pubmed: 19236023
J Mass Spectrom. 2019 Jun;54(6):567-582
pubmed: 31083780
Methods Mol Biol. 2019;1859:253-260
pubmed: 30421234
Anal Chem. 2017 Oct 3;89(19):10397-10406
pubmed: 28914531
Kidney Int. 2016 Mar;89(3):539-45
pubmed: 26880450
F1000Res. 2017 Sep 6;6:
pubmed: 29043062
Electrophoresis. 2018 May;39(9-10):1222-1232
pubmed: 29292828
Anal Chem. 2005 Jan 1;77(1):78-84
pubmed: 15623281
Chem Rev. 2013 Apr 10;113(4):2437-68
pubmed: 23506082
Anal Chem. 2013 Nov 19;85(22):10664-9
pubmed: 24195601
Nephrol Dial Transplant. 2017 Dec 01;32(12):2079-2089
pubmed: 27984204
Electrophoresis. 2010 Jul;31(14):2311-8
pubmed: 20568260
Anal Bioanal Chem. 2017 Jul;409(18):4383-4393
pubmed: 28484810
Sci Rep. 2016 Oct 03;6:34453
pubmed: 27694997
Anal Chem. 2020 Apr 7;92(7):5013-5022
pubmed: 32167758
Anal Chem. 2017 Sep 5;89(17):9048-9055
pubmed: 28763190
Bioinformatics. 2010 Apr 1;26(7):966-8
pubmed: 20147306
J Am Soc Mass Spectrom. 2017 Apr;28(4):709-723
pubmed: 28116700
PLoS One. 2018 Jan 18;13(1):e0191230
pubmed: 29346414
Analyst. 2017 Dec 18;143(1):16-20
pubmed: 29215666
Analyst. 2019 Jan 28;144(3):892-900
pubmed: 30542678
Anal Chem. 2006 Sep 15;78(18):6573-82
pubmed: 16970336
Anal Chem. 2011 Sep 1;83(17):6810-7
pubmed: 21809850
Anal Chim Acta. 2018 Nov 22;1032:178-187
pubmed: 30143215
Electrophoresis. 2021 Feb;42(4):342-349
pubmed: 32744343
Anal Chem. 2019 Feb 5;91(3):2329-2336
pubmed: 30570251
Sci Rep. 2019 Jan 28;9(1):806
pubmed: 30692602
Electrophoresis. 2016 Apr;37(7-8):1007-14
pubmed: 26593113