Associations of Body Mass Index, Weight Change, Physical Activity, and Sedentary Behavior With Endometrial Cancer Risk Among Japanese Women: The Japan Collaborative Cohort Study.
body mass index
cohort study
endometrial carcinoma
exercise
sedentary behavior
Journal
Journal of epidemiology
ISSN: 1349-9092
Titre abrégé: J Epidemiol
Pays: Japan
ID NLM: 9607688
Informations de publication
Date de publication:
05 12 2021
05 12 2021
Historique:
pubmed:
24
9
2020
medline:
25
12
2021
entrez:
23
9
2020
Statut:
ppublish
Résumé
The impact of weight change, physical activity, and sedentary behavior on endometrial cancer risk among the Asian population is uncertain. We investigated the association of those factors with endometrial cancer risk among Japanese women with a low body mass index level. We performed a large-scale nationwide cohort study consisting of 33,801 female participants aged 40-79 years. The Cox proportional hazards model was used to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs) of incident endometrial cancer. The mean body mass index of participants was 22.8 kg/m Overweight and weight gain were positively associated with the risk of endometrial cancer, while worksite physical activity was inversely associated with the risk.
Sections du résumé
BACKGROUND
The impact of weight change, physical activity, and sedentary behavior on endometrial cancer risk among the Asian population is uncertain. We investigated the association of those factors with endometrial cancer risk among Japanese women with a low body mass index level.
METHODS
We performed a large-scale nationwide cohort study consisting of 33,801 female participants aged 40-79 years. The Cox proportional hazards model was used to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs) of incident endometrial cancer.
RESULTS
The mean body mass index of participants was 22.8 kg/m
CONCLUSIONS
Overweight and weight gain were positively associated with the risk of endometrial cancer, while worksite physical activity was inversely associated with the risk.
Identifiants
pubmed: 32963209
doi: 10.2188/jea.JE20200145
pmc: PMC8593582
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
621-627Références
J Clin Oncol. 2013 Jul 10;31(20):2607-18
pubmed: 23733771
Obstet Gynecol. 2017 Jun;129(6):1059-1067
pubmed: 28486362
Lancet. 2016 Apr 2;387(10026):1377-1396
pubmed: 27115820
Cancer Causes Control. 2007 May;18(4):399-413
pubmed: 17297555
J Natl Cancer Inst. 2015 Mar 10;107(2):
pubmed: 25757865
Breast Cancer Res. 2015 Nov 05;17(1):139
pubmed: 26541144
CA Cancer J Clin. 2001 Jan-Feb;51(1):38-75; quiz 77-80
pubmed: 11577479
Cell Physiol Biochem. 2015;37(2):735-46
pubmed: 26356264
PLoS One. 2014 Aug 25;9(8):e105709
pubmed: 25153314
Int J Obes Relat Metab Disord. 2003 Feb;27(2):247-52
pubmed: 12587006
Lancet. 2004 Jan 10;363(9403):157-63
pubmed: 14726171
Eur J Clin Nutr. 2015 Apr;69(4):462-6
pubmed: 25469462
J Natl Cancer Inst. 2014 Jun 16;106(7):
pubmed: 24935969
J Natl Cancer Inst. 2018 Apr 1;110(4):354-361
pubmed: 29045681
Lancet Oncol. 2015 Sep;16(9):1061-1070
pubmed: 26254030
Eur J Epidemiol. 2015 May;30(5):397-412
pubmed: 25800123
Int J Biol Markers. 2014 Mar 24;29(1):e21-9
pubmed: 24170556
J Epidemiol. 2013;23(3):227-32
pubmed: 23583921
Nat Rev Endocrinol. 2014 Aug;10(8):455-465
pubmed: 24935119
BMJ. 2017 Oct 26;359:j4511
pubmed: 29074629
Eur J Cancer Prev. 2019 May;28(3):196-202
pubmed: 29672353
Eur J Cancer Prev. 2016 Jul;25(4):329-34
pubmed: 26075656
BMJ. 2017 Feb 28;356:j477
pubmed: 28246088
J Epidemiol. 2001 Sep;11(5):211-8
pubmed: 11579928
Cell Metab. 2017 Mar 7;25(3):581-592
pubmed: 28273480
Steroids. 2015 Jul;99(Pt A):8-10
pubmed: 25555473
Maturitas. 1996 Nov;25(3):201-7
pubmed: 8981337
Am J Prev Med. 2011 Aug;41(2):228-35
pubmed: 21767731
Endocr Relat Cancer. 2015 Dec;22(6):R365-86
pubmed: 26373570
Cancer Causes Control. 2010 Jul;21(7):1105-16
pubmed: 20336482
Gynecol Oncol. 2010 Jul;118(1):24-8
pubmed: 20400173
Int J Cancer. 2014 Jun 1;134(11):2707-16
pubmed: 24213924
Med Sci Monit. 2012 Dec;18(12):RA173-80
pubmed: 23197245
Cancer Causes Control. 2010 Sep;21(9):1407-16
pubmed: 20431936