Anticonvulsant Effect of Alcea aucheri on Pentylenetetrazole and Maximal Electroshock Seizures in Mice.
Alcea aucheri
Maximal electroshock seizure
Mice
Pentylenetetrazole
Seizure threshold
Journal
Basic and clinical neuroscience
ISSN: 2008-126X
Titre abrégé: Basic Clin Neurosci
Pays: Iran
ID NLM: 101575211
Informations de publication
Date de publication:
Historique:
received:
21
09
2019
revised:
10
10
2019
accepted:
11
12
2019
entrez:
23
9
2020
pubmed:
24
9
2020
medline:
24
9
2020
Statut:
ppublish
Résumé
This study was designed to investigate the possible anticonvulsant effect of acute administration of an aqueous extract of flowers of Alcea aucheri (EFA) in two in vivo seizure models. Seizures were induced in male adult Swiss mice by administration of Pentylenetetrazol (PTZ) or Maximal Electroshock (MES). Mice were randomly subjected to receive saline, EFA (8.75-175 mg.kg EFA (175 mg.kg These findings provide evidence of a possible anticonvulsant effect of A. aucheri in PTZ and MES seizure models in mice.
Identifiants
pubmed: 32963729
doi: 10.32598/bcn.11.2.2064.1
pii: bcn-11-369
pmc: PMC7502187
doi:
Types de publication
Journal Article
Langues
eng
Pagination
369-377Informations de copyright
Copyright© 2020 Iranian Neuroscience Society.
Déclaration de conflit d'intérêts
Conflict of interest The authors declared no competing interest.
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