Personalised exhaled nitric oxygen fraction (
Journal
ERJ open research
ISSN: 2312-0541
Titre abrégé: ERJ Open Res
Pays: England
ID NLM: 101671641
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
07
01
2020
accepted:
24
03
2020
entrez:
23
9
2020
pubmed:
24
9
2020
medline:
24
9
2020
Statut:
epublish
Résumé
The aim of this study was to identify patients who benefit most from exhaled nitric oxide fraction ( We used data from 179 adults with asthma from a 12-month primary care randomised controlled trial with 3-monthly assessments of We found a difference between the Ca and FCa strategy for the mean dosage of beclomethasone strategy of 223 µg (95% CI 6-439), p=0.04) and for the total costs of asthma medication a mean reduction of US$159 (95% CI US$33-285), p=0.03) in patients with a low baseline In primary care,
Sections du résumé
BACKGROUND
BACKGROUND
The aim of this study was to identify patients who benefit most from exhaled nitric oxide fraction (
METHODS
METHODS
We used data from 179 adults with asthma from a 12-month primary care randomised controlled trial with 3-monthly assessments of
RESULTS
RESULTS
We found a difference between the Ca and FCa strategy for the mean dosage of beclomethasone strategy of 223 µg (95% CI 6-439), p=0.04) and for the total costs of asthma medication a mean reduction of US$159 (95% CI US$33-285), p=0.03) in patients with a low baseline
CONCLUSIONS
CONCLUSIONS
In primary care,
Identifiants
pubmed: 32963989
doi: 10.1183/23120541.00351-2019
pii: 00351-2019
pmc: PMC7487343
pii:
doi:
Types de publication
Journal Article
Langues
eng
Informations de copyright
Copyright ©ERS 2020.
Déclaration de conflit d'intérêts
Conflict of interest: S. Boer has nothing to disclose. Conflict of interest: P.J. Honkoop has nothing to disclose. Conflict of interest: R.J.B. Loijmans has nothing to disclose. Conflict of interest: J.B. Snoeck-Stroband has nothing to disclose. Conflict of interest: W.J.J. Assendelft has nothing to disclose. Conflict of interest: T.R.J. Schermer reports projects grants for the study from the Netherlands Organisation for Health Research and Development, and the Dutch Lung Foundation, during the conduct of the study. Conflict of interest: J.K. Sont reports an unrestricted research grant from GSK Netherlands outside the submitted work.
Références
BMC Pulm Med. 2011 Nov 24;11:53
pubmed: 22114896
Lancet. 2008 Sep 20;372(9643):1065-72
pubmed: 18805335
Am J Respir Crit Care Med. 2005 Apr 15;171(8):912-30
pubmed: 15817806
Lancet. 2006 Aug 26;368(9537):780-93
pubmed: 16935689
J Asthma. 2008 Sep;45(7):523-31
pubmed: 18773320
Chest. 2008 Apr;133(4):837-9
pubmed: 18398112
Respir Med. 2013 Jul;107(7):943-52
pubmed: 23601567
Am J Respir Crit Care Med. 2009 Jul 1;180(1):59-99
pubmed: 19535666
Am J Respir Crit Care Med. 2000 Aug;162(2 Pt 1):490-6
pubmed: 10934076
J Allergy Clin Immunol. 2011 Feb;127(2):355-60
pubmed: 21281866
Allergy Asthma Proc. 2018 Jan 1;39(1):27-35
pubmed: 29279057
Allergy Asthma Proc. 2018 Sep 13;39(5):338-344
pubmed: 30103840
Am J Respir Crit Care Med. 2009 Jan 15;179(2):93-7
pubmed: 18931330
Respir Med. 2006 Apr;100(4):616-21
pubmed: 16226443
Respir Med. 2012 Aug;106(8):1158-63
pubmed: 22682550
J Allergy Clin Immunol. 2015 Mar;135(3):682-8.e11
pubmed: 25174865
Am J Respir Crit Care Med. 2007 Aug 1;176(3):231-7
pubmed: 17496226
Am J Respir Crit Care Med. 2005 Oct 1;172(7):831-6
pubmed: 15976380
Respir Res. 2006 Apr 20;7:67
pubmed: 16626491
Am J Respir Crit Care Med. 2011 Sep 1;184(5):602-15
pubmed: 21885636
Prim Care Respir J. 2009 Dec;18(4):320-7
pubmed: 19888541
Thorax. 1996 May;51(5):496-502
pubmed: 8711677
Eur Respir J. 2014 Feb;43(2):343-73
pubmed: 24337046
Eur Respir J. 2016 Feb;47(2):410-9
pubmed: 26828055
Am Rev Respir Dis. 1993 Apr;147(4):832-8
pubmed: 8466117
Clin Sci (Lond). 2017 May 1;131(10):1027-1043
pubmed: 28487412
Thorax. 2014 Nov;69 Suppl 1:1-192
pubmed: 25323740
N Engl J Med. 2005 May 26;352(21):2163-73
pubmed: 15914548
Am J Respir Crit Care Med. 2001 Sep 1;164(5):738-43
pubmed: 11549525
Cochrane Database Syst Rev. 2016 Sep 01;9:CD011440
pubmed: 27580628