"It's hard for us men to go to the clinic. We naturally have a fear of hospitals." Men's risk perceptions, experiences and program preferences for PrEP: A mixed methods study in Eswatini.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2020
Historique:
received: 17 09 2019
accepted: 27 07 2020
entrez: 23 9 2020
pubmed: 24 9 2020
medline: 29 10 2020
Statut: epublish

Résumé

Few studies on HIV Pre-Exposure Prophylaxis (PrEP) have focused on men who have sex with women. We present findings from a mixed-methods study in Eswatini, the country with the highest HIV prevalence in the world (27%). Our findings are based on risk assessments, in-depth interviews and focus-group discussions which describe men's motivations for taking up or declining PrEP. Quantitatively, men self-reported starting PrEP because they had multiple or sero-discordant partners or did not know the partner's HIV-status. Men's self-perception of risk was echoed in the qualitative data, which revealed that the hope of facilitated sexual performance or relations, a preference for pills over condoms and the desire to protect themselves and others also played a role for men to initiate PrEP. Trust and mistrust and being able or unable to speak about PrEP with partner(s) were further considerations for initiating or declining PrEP. Once on PrEP, men's sexual behavior varied in terms of number of partners and condom use. Men viewed daily pill-taking as an obstacle to starting PrEP. Side-effects were a major reason for men to discontinue PrEP. Men also worried that taking anti-retroviral drugs daily might leave them mistaken for a person living with HIV, and viewed clinic-based PrEP education and initiation processes as a further obstacle. Given that men comprise only 29% of all PrEP users in Eswatini, barriers to men's uptake of PrEP will need to be addressed, in terms of more male-friendly services as well as trialing community-based PrEP education and service delivery.

Identifiants

pubmed: 32966307
doi: 10.1371/journal.pone.0237427
pii: PONE-D-19-26173
pmc: PMC7510987
doi:

Substances chimiques

Anti-HIV Agents 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0237427

Subventions

Organisme : NCATS NIH HHS
ID : KL2 TR003143
Pays : United States

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

World J AIDS. 2015 Mar;5(2):10-20
pubmed: 26767149
Lancet HIV. 2017 Mar;4(3):e113-e121
pubmed: 27956187
AIDS. 2015 Jul 17;29(11):1401-9
pubmed: 26091299
BMC Public Health. 2019 Jul 24;19(1):996
pubmed: 31340785
AIDS Behav. 2015 Dec;19(12):2234-44
pubmed: 25735243
Afr J Reprod Health. 2001 Dec;5(3):175-95
pubmed: 12471940
AIDS. 2015 Jun 19;29(10):1123-5
pubmed: 26035315
PLoS One. 2013 Dec 18;8(12):e81997
pubmed: 24367497
PLoS One. 2007 Sep 19;2(9):e875
pubmed: 17878928
AIDS. 2018 Jul 17;32(11):1541-1542
pubmed: 29794832
AIDS Behav. 2017 May;21(5):1236-1246
pubmed: 28108878
Infection. 2016 Apr;44(2):151-8
pubmed: 26471511
PLoS Med. 2017 Nov 28;14(11):e1002463
pubmed: 29182641
Swiss Med Wkly. 2014 Apr 10;144:w13961
pubmed: 24723302
Soc Sci Med. 2000 May;50(10):1385-401
pubmed: 10741575
Trop Med Int Health. 2015 Dec;20(12):1634-5
pubmed: 26325025
Curr HIV/AIDS Rep. 2018 Apr;15(2):190-197
pubmed: 29460223
Int J STD AIDS. 2017 Jul;28(8):814-821
pubmed: 27707954
Am J Mens Health. 2019 Jan-Feb;13(1):1557988319827396
pubmed: 30819060
J Int AIDS Soc. 2019 Oct;22(10):e25408
pubmed: 31651098
Glob Health Action. 2014 Sep 30;7:24795
pubmed: 25280736
Lancet HIV. 2017 Sep;4(9):e402-e410
pubmed: 28747274
Clin Infect Dis. 2018 Aug 16;67(5):676-686
pubmed: 29509889
AIDS Behav. 2016 Jul;20(7):1461-9
pubmed: 25835463
Med Anthropol Q. 1997 Jun;11(2):147-63
pubmed: 9186958
PLoS One. 2018 Feb 8;13(2):e0191251
pubmed: 29420549
J Health Psychol. 2002 May;7(3):253-67
pubmed: 22114249
AIDS Behav. 2018 Apr;22(4):1096-1099
pubmed: 29243109
BMJ. 2006 Mar 11;332(7541):605-7
pubmed: 16528088
Am J Public Health. 2010 Mar;100(3):435-45
pubmed: 20075321
Sex Transm Dis. 2008 Dec;35(12):1002-8
pubmed: 19051397
J Acquir Immune Defic Syndr. 2017 Mar 1;74(3):285-292
pubmed: 28187084
Curr HIV/AIDS Rep. 2019 Apr;16(2):141-150
pubmed: 30796608
Trop Med Int Health. 2011 Jul;16(7):828-9
pubmed: 21418449
AIDS. 2014 Sep 10;28(14):2133-45
pubmed: 25062091
PLoS One. 2012;7(11):e50871
pubmed: 23226413
Science. 2013 Feb 22;339(6122):961-5
pubmed: 23430655
PLoS Med. 2015 Nov 24;12(11):e1001905; discussion e1001905
pubmed: 26599699
AIDS Educ Prev. 2012 Oct;24(5):408-21
pubmed: 23016502
Sex Health. 2016 May 26;:
pubmed: 27224942
Lancet HIV. 2017 Feb;4(2):e83-e92
pubmed: 27863998
BMJ Open. 2014 Nov 20;4(11):e005717
pubmed: 25412863
PLoS Med. 2016 Aug 23;13(8):e1002099
pubmed: 27552090
PLoS One. 2010 Jul 30;5(7):e11922
pubmed: 20689602
AIDS Care. 2020 Feb;32(2):267-273
pubmed: 31437021
AIDS Behav. 2017 May;21(5):1325-1335
pubmed: 27900502
Cult Health Sex. 2011 May;13(5):545-59
pubmed: 21390949
Cult Health Sex. 2005 Nov-Dec;7(6):585-98
pubmed: 16864224
AIDS Care. 2018 Oct;30(10):1311-1314
pubmed: 29914270
N Engl J Med. 2012 Aug 2;367(5):399-410
pubmed: 22784037
AIDS Behav. 2019 Jul;23(7):1708-1720
pubmed: 30306439
Curr HIV/AIDS Rep. 2007 Dec;4(4):165-72
pubmed: 18366947
Glob Public Health. 2020 Sep;15(9):1337-1348
pubmed: 32207661
J Acquir Immune Defic Syndr. 2013 Sep 1;64(1):87-94
pubmed: 23481668
J Acquir Immune Defic Syndr. 2012 Apr 15;59(5):463-8
pubmed: 22267018
Med J Aust. 2006 Jan 16;184(2):81-3
pubmed: 16411874
BMJ Glob Health. 2018 Sep 10;3(5):e000837
pubmed: 30233833
AIDS. 2016 Jul 31;30(12):1973-83
pubmed: 27149090
AIDS. 2015 Jul 17;29(11):1277-85
pubmed: 26103095
Indian J Med Res. 2013 Jun;137(6):1061-71
pubmed: 23852287
AIDS Patient Care STDS. 2015 Aug;29(8):423-9
pubmed: 26083143
AIDS. 2019 Jun 1;33 Suppl 1:S45-S52
pubmed: 31397722

Auteurs

Astrid Berner-Rodoreda (A)

Institute of Global Health, Ruprecht-Karls-Universität, Heidelberg, Germany.

Pascal Geldsetzer (P)

Institute of Global Health, Ruprecht-Karls-Universität, Heidelberg, Germany.
Division of Primary Care and Population Health, Department of Medicine, Stanford University, Stanford, California, United States of America.

Kate Bärnighausen (K)

Institute of Global Health, Ruprecht-Karls-Universität, Heidelberg, Germany.
University of the Witwatersrand School of Public Health, Johannesburg, South Africa.

Anita Hettema (A)

Clinton Health Access Initiative Swaziland, Mbabane, Eswatini.

Till Bärnighausen (T)

Institute of Global Health, Ruprecht-Karls-Universität, Heidelberg, Germany.
Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.

Sindy Matse (S)

Eswatini Ministry of Health, Mbabane, Eswatini.

Shannon A McMahon (SA)

Institute of Global Health, Ruprecht-Karls-Universität, Heidelberg, Germany.
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH