Characterization of Bone Marrow and Wharton's Jelly Mesenchymal Stromal Cells Response on Multilayer Braided Silk and Silk/PLCL Scaffolds for Ligament Tissue Engineering.

PLCL biocompatibility braided scaffold ligament tissue engineering silk stromal cells

Journal

Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357

Informations de publication

Date de publication:
22 Sep 2020
Historique:
received: 31 08 2020
revised: 18 09 2020
accepted: 18 09 2020
entrez: 25 9 2020
pubmed: 26 9 2020
medline: 26 9 2020
Statut: epublish

Résumé

(1) Background: A suitable scaffold with adapted mechanical and biological properties for ligament tissue engineering is still missing. (2) Methods: Different scaffold configurations were characterized in terms of morphology and a mechanical response, and their interactions with two types of stem cells (Wharton's jelly mesenchymal stromal cells (WJ-MSCs) and bone marrow mesenchymal stromal cells (BM-MSCs)) were assessed. The scaffold configurations consisted of multilayer braids with various number of silk layers (

Identifiants

pubmed: 32971891
pii: polym12092163
doi: 10.3390/polym12092163
pmc: PMC7569883
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Conseil régional du Grand Est
ID : AAP-010-078
Organisme : Centre National de la Recherche Scientifique
ID : special funding "material by design"

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Auteurs

Xing Liu (X)

CNRS UMR 7365 IMoPA - Université de Lorraine, 54500 Vandœuvre-lès-Nancy, France.

Adrien Baldit (A)

Université de Lorraine, CNRS, Arts et Métiers ParisTech, LEM3, F-57000 Metz, France.

Emilie de Brosses (E)

Université de Lorraine, CNRS, Arts et Métiers ParisTech, LEM3, F-57000 Metz, France.

Frédéric Velard (F)

Université Reims Champagne-Ardenne, BIOS EA 4691 1, avenue du Maréchal Juin, 51095 Reims, France.

Ghislaine Cauchois (G)

CNRS UMR 7365 IMoPA - Université de Lorraine, 54500 Vandœuvre-lès-Nancy, France.

Yun Chen (Y)

Department of Biomedical Engineering, School of Basic Medical Science, Wuhan University, Wuhan 430000, China.

Xiong Wang (X)

CNRS UMR 7365 IMoPA - Université de Lorraine, 54500 Vandœuvre-lès-Nancy, France.

Natalia de Isla (N)

CNRS UMR 7365 IMoPA - Université de Lorraine, 54500 Vandœuvre-lès-Nancy, France.

Cédric Laurent (C)

Université de Lorraine, CNRS, Arts et Métiers ParisTech, LEM3, F-54000 Nancy, France.

Classifications MeSH