Evidence That Cannabis Exposure, Abuse, and Dependence Are Related to Glutamate Metabolism and Glial Function in the Anterior Cingulate Cortex: A

anterior cingulate cortex cannabis glial glutamate imaging magnetic resonance spectroscopy myo-inositol substance use disorder

Journal

Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006

Informations de publication

Date de publication:
2020
Historique:
received: 06 04 2020
accepted: 20 07 2020
entrez: 25 9 2020
pubmed: 26 9 2020
medline: 26 9 2020
Statut: epublish

Résumé

There is evidence that long-term cannabis use is associated with alterations to glutamate neurotransmission and glial function. In this study, 26 long-term cannabis users (males=65.4%) and 47 non-cannabis using healthy controls (males=44.6%) underwent proton magnetic resonance spectroscopy (

Identifiants

pubmed: 32973572
doi: 10.3389/fpsyt.2020.00764
pmc: PMC7468488
doi:

Types de publication

Journal Article

Langues

eng

Pagination

764

Subventions

Organisme : NIMH NIH HHS
ID : R01 MH113564
Pays : United States

Informations de copyright

Copyright © 2020 Watts, Garani, Da Silva, Lalang, Chavez and Mizrahi.

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Auteurs

Jeremy J Watts (JJ)

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Department of Pharmacology & Toxicology, University of Toronto, Toronto, ON, Canada.

Ranjini Garani (R)

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Department of Pharmacology & Toxicology, University of Toronto, Toronto, ON, Canada.

Tania Da Silva (T)

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.

Nittha Lalang (N)

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Department of Pharmacology & Toxicology, University of Toronto, Toronto, ON, Canada.

Sofia Chavez (S)

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.

Romina Mizrahi (R)

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Department of Pharmacology & Toxicology, University of Toronto, Toronto, ON, Canada.
Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.

Classifications MeSH