Evaluation of Murine Macrophage Cytokine Production After In Vivo Morphine Treatment.

Analgesics, Opioid / immunology Animals Cytokines / analysis Immune System Phenomena Immunologic Factors / analysis Immunomodulation / drug effects Macrophages / drug effects Mice Morphine / adverse effects Primary Cell Culture / methods Receptors, Opioid / immunology
Cytokines Lipopolysaccharide Morphine Murine macrophages Opioid-induced immunosuppression

Journal

Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969

Informations de publication

Date de publication:
2021
Historique:
entrez: 25 9 2020
pubmed: 26 9 2020
medline: 23 3 2021
Statut: ppublish

Résumé

The discovery of opioid receptor expression on immune cells has originated a large research activity on the possible modulation by opioid drugs of immune system responses. In this chapter we describe an easy methodology useful to obtain information about the potential immunomodulatory activity of opioid drugs. An in vivo treatment schedule is used, and macrophages are studied for their ability to release different cytokines.

Identifiants

DOI: 10.1007/978-1-0716-0884-5_18 PMID: 32975801
pubmed: 32975801
doi: 10.1007/978-1-0716-0884-5_18
doi:

Substances chimiques

Analgesics, Opioid 0
Cytokines 0
Immunologic Factors 0
Receptors, Opioid 0
Morphine 76I7G6D29C

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

199-207

Auteurs

Silvia Franchi (S)

Department of Pharmacological and Biomolecular Science, University of Milano, Milan, Italy.

Mara Castelli (M)

Department of Pharmacological and Biomolecular Science, University of Milano, Milan, Italy.

Sarah Moretti (S)

Department of Pharmacological and Biomolecular Science, University of Milano, Milan, Italy.

Alberto Panerai (A)

Department of Pharmacological and Biomolecular Science, University of Milano, Milan, Italy.

Paola Sacerdote (P)

Department of Pharmacological and Biomolecular Science, University of Milano, Milan, Italy. paola.sacerdote@unimi.it.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Dépresseurs du système nerveux central › Stupéfiants › Analgésiques morphiniques › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Eucaryotes › Animaux › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Phénomènes du système immunitaire › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunomodulation › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Phénanthrènes › Morphinanes › Dérivés de la morphine › Morphine › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Techniques d'investigation › Techniques in vitro › Techniques de culture › Techniques de culture cellulaire › Culture de cellules primaires › Evaluation of Murine Macrophage Cytokine...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur aux neuropeptides › Récepteurs aux opioïdes › Evaluation of Murine Macrophage Cytokine...