The Accuracy of Repeated Sleep Studies in OSA: A Longitudinal Observational Study With 14 Nights of Oxygen Saturation Monitoring.

Diagnostic Errors / prevention & control Dimensional Measurement Accuracy Female Humans Male Middle Aged Monitoring, Physiologic / methods Oximetry / methods Oxygen / analysis Polysomnography / methods Prospective Studies Sleep Apnea, Obstructive / diagnosis
OSA apnea-hypopnea index first night effect night-to-night variability oxygen desaturation index pulse oximetry sensitivity

Journal

Chest
ISSN: 1931-3543
Titre abrégé: Chest
Pays: United States
ID NLM: 0231335

Informations de publication

Date de publication:
03 2021
Historique:
received: 20 03 2020
revised: 12 08 2020
accepted: 04 09 2020
pubmed: 28 9 2020
medline: 25 9 2021
entrez: 27 9 2020
Statut: ppublish

Résumé

Strong evidence exists for clinically relevant night-to-night variability of respiratory events in patients with suspected OSA. How many sleep study nights are required to diagnose OSA accurately? Patients with suspected OSA underwent up to 14 nights of pulse oximetry (PO) at home and one night of in-hospital respiratory polygraphy (RP). The accuracy of each of the 13 sleep study nights was analyzed using the mean oxygen desaturation index 3% (ODI One hundred three patients underwent in-hospital RP. Using only the results of the RP, 19.7% were misdiagnosed using an ODI One single night of in-hospital RP may miss relevant OSA. Multiple study nights, for example, using ambulatory oxygen saturation monitoring, increase accuracy for diagnosing moderate OSA. ClinicalTrials.gov; No.: NCT03819361; URL: www.clinicaltrials.gov.

Sections du résumé

BACKGROUND
Strong evidence exists for clinically relevant night-to-night variability of respiratory events in patients with suspected OSA.
RESEARCH QUESTION
How many sleep study nights are required to diagnose OSA accurately?
STUDY DESIGN AND METHODS
Patients with suspected OSA underwent up to 14 nights of pulse oximetry (PO) at home and one night of in-hospital respiratory polygraphy (RP). The accuracy of each of the 13 sleep study nights was analyzed using the mean oxygen desaturation index 3% (ODI
RESULTS
One hundred three patients underwent in-hospital RP. Using only the results of the RP, 19.7% were misdiagnosed using an ODI
INTERPRETATION
One single night of in-hospital RP may miss relevant OSA. Multiple study nights, for example, using ambulatory oxygen saturation monitoring, increase accuracy for diagnosing moderate OSA.
TRIAL REGISTRY
ClinicalTrials.gov; No.: NCT03819361; URL: www.clinicaltrials.gov.

Identifiants

DOI: 10.1016/j.chest.2020.09.098 PMID: 32980370
pubmed: 32980370
pii: S0012-3692(20)34520-7
doi: 10.1016/j.chest.2020.09.098
pii:
doi:

Substances chimiques

Oxygen S88TT14065

Banques de données

ClinicalTrials.gov
['NCT03819361']

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1222-1231

Informations de copyright

Copyright © 2020 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

Auteurs

Maurice Roeder (M)

Department of Pulmonology, University Hospital Zurich, Zurich, Switzerland.

Noriane A Sievi (NA)

Department of Pulmonology, University Hospital Zurich, Zurich, Switzerland.

Matteo Bradicich (M)

Department of Pulmonology, University Hospital Zurich, Zurich, Switzerland.

Fabian A Grewe (FA)

Department of Pulmonology, University Hospital Zurich, Zurich, Switzerland.

Sandra Siegfried (S)

Department of Biostatistics and Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.

Thomas Gaisl (T)

Department of Pulmonology, University Hospital Zurich, Zurich, Switzerland.

Malcolm Kohler (M)

Department of Pulmonology, University Hospital Zurich, Zurich, Switzerland; Centre for Interdisciplinary Sleep Research, University of Zurich, Zurich, Switzerland. Electronic address: malcolm.kohler@usz.ch.

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Classifications MeSH

questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Erreurs médicales › Erreurs de diagnostic › The Accuracy of Repeated Sleep Studies in OSA:...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Reproductibilité des résultats › Précision de la mesure dimensionnelle › The Accuracy of Repeated Sleep Studies in OSA:...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Accuracy of Repeated Sleep Studies in OSA:...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › The Accuracy of Repeated Sleep Studies in OSA:...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Monitorage physiologique › The Accuracy of Repeated Sleep Studies in OSA:...
questionsmedicales.fr › Techniques d'investigation › Techniques de laboratoire clinique › Tests de chimie clinique › Analyse chimique du sang › Gazométrie sanguine › Oxymétrie › The Accuracy of Repeated Sleep Studies in OSA:...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Oxygène › The Accuracy of Repeated Sleep Studies in OSA:...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Monitorage physiologique › Polysomnographie › The Accuracy of Repeated Sleep Studies in OSA:...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › The Accuracy of Repeated Sleep Studies in OSA:...
questionsmedicales.fr › Maladies du système nerveux › Syndromes d'apnées du sommeil › Syndrome d'apnées obstructives du sommeil › The Accuracy of Repeated Sleep Studies in OSA:...