Methods for prospectively incorporating gender into health sciences research.


Journal

Journal of clinical epidemiology
ISSN: 1878-5921
Titre abrégé: J Clin Epidemiol
Pays: United States
ID NLM: 8801383

Informations de publication

Date de publication:
01 2021
Historique:
received: 26 06 2020
revised: 27 07 2020
accepted: 15 08 2020
pubmed: 28 9 2020
medline: 7 9 2021
entrez: 27 9 2020
Statut: ppublish

Résumé

Numerous studies have demonstrated that sex (a biological variable) and gender (a psychosocial construct) impact health and have discussed the mechanisms that may explain these relationships. Funding agencies have called for all health researchers to incorporate sex and gender into their studies; however, the way forward has been unclear to many, particularly due to the varied definition of gender. We argue that just as there is no standardized definition of gender, there can be no standardized measurement thereof. However, numerous measurable gender-related variables may influence individual or population-level health through various pathways. The initial question should guide the selection of specific gender-related variables based on their relevance to the study, to prospectively incorporate gender into research. We outline various methods to provide clarification on how to incorporate gender into the design of prospective clinical and epidemiological studies as well as methods for statistical analysis.

Identifiants

pubmed: 32980428
pii: S0895-4356(20)31104-5
doi: 10.1016/j.jclinepi.2020.08.018
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

191-197

Subventions

Organisme : Austrian Science Fund FWF
ID : I 4209
Pays : Austria

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Christina P Tadiri (CP)

Research Institute of McGill University Health Centre, Division of Clinical Epidemiology McGill University, Montréal, Quebec, Canada.

Valeria Raparelli (V)

Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.

Michal Abrahamowicz (M)

Research Institute of McGill University Health Centre, Division of Clinical Epidemiology McGill University, Montréal, Quebec, Canada.

Alexandra Kautzy-Willer (A)

Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria.

Karolina Kublickiene (K)

Department of Renal Medicine, Institution for Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.

Maria-Trinidad Herrero (MT)

Clinical and Experimental Neuroscience, Institutes for Aging Research and Bio-Health Research of Murcia. School of Medicine, University of Murcia, Murcia, Spain.

Colleen M Norris (CM)

Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada; Cardiovascular and Stroke Strategic Clinical Network, Alberta Health Services, Edmonton, Alberta, Canada.

Louise Pilote (L)

Research Institute of McGill University Health Centre, Division of Clinical Epidemiology McGill University, Montréal, Quebec, Canada. Electronic address: louise.pilote@mcgill.ca.

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