Alkaloids of
AChE
AChE, Acetylcholinesterase
AE, alkaloid extract
ATCI, acetylthiocholine iodide
Alkaloids
Alzheimer's disease
Amaryllidaceae
BTCI, butyrylthiocholine iodide
BuChE
BuChE, butyrylcholinesterase
CD, circular dichroism
DTNB, (5,5′-dithio-bis-[2-nitrobenzoic acid])
Et2O, diethyl ether
EtOAc, ethyl acetate
GAL, galanthamine
GC-MS, gas chromatography coupled to mass spectrometry
IUCN, International Union for Conservation of Nature
MS, mass spectrometry
MeOH, methanol
Molecular docking
NMR, nuclear magnetic resonance
Phaedranassa
UV, ultraviolet
Journal
South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges
ISSN: 0254-6299
Titre abrégé: S Afr J Bot
Pays: South Africa
ID NLM: 100955699
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
09
07
2020
revised:
04
09
2020
accepted:
07
09
2020
pubmed:
29
9
2020
medline:
29
9
2020
entrez:
28
9
2020
Statut:
ppublish
Résumé
Alzheimer's disease is considered the most common cause of dementia and, in an increasingly aging population worldwide, the quest for treatment is a priority. Amaryllidaceae alkaloids are of main interest because of their cholinesterase inhibition potential, which is the main palliative treatment available for this disease. We evaluated the alkaloidal profile and the
Identifiants
pubmed: 32982003
doi: 10.1016/j.sajb.2020.09.007
pii: S0254-6299(20)31063-2
pmc: PMC7500283
doi:
Types de publication
Journal Article
Langues
eng
Pagination
91-99Informations de copyright
© 2020 SAAB. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
The authors have declared that there is no conflict of interest.
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