Association of working conditions including digital technology use and systemic inflammation among employees: study protocol for a systematic review.
Digitalization
Health
Immune system
Inflammation
Inflammatory markers
Job
Occupational stress
Technostress
Work
Working conditions
Journal
Systematic reviews
ISSN: 2046-4053
Titre abrégé: Syst Rev
Pays: England
ID NLM: 101580575
Informations de publication
Date de publication:
28 09 2020
28 09 2020
Historique:
received:
12
03
2020
accepted:
21
08
2020
entrez:
29
9
2020
pubmed:
30
9
2020
medline:
25
6
2021
Statut:
epublish
Résumé
With the dynamic advancement of digitalization, working environments are changing and risk for employee stress may be increasing. Work stress has been associated with a dysregulation of inflammatory processes as a component of immune function. Systemic low-grade inflammation is discussed as a key player in the relation between stress exposure and chronic illness, such as cardiovascular diseases. The objective of this investigation will be to evaluate the association of working conditions including digital technology use and systemic inflammation among employees. We designed and registered a study protocol for a systematic review of randomized controlled trials and prospective non-randomized studies (e.g., cohort, interrupted time series, or before-after studies). We will include studies conducted among adult workers reporting associations of working conditions and inflammatory activity. The outcome will be biomarkers of systemic low-grade inflammation on cell, plasma molecule and intracellular level, such as C-reactive protein, or different types of leukocytes, cytokines, etc. Literature searches will be conducted in several electronic databases (from January 1982 onwards), including PubMed/MEDLINE, Embase, PsycINFO, Web of Science, and CENTRAL. Two reviewers will independently screen all retrieved records, full-text articles, and extract data. The study methodological quality (or bias) will be appraised using appropriate tools. Our results will be described qualitatively. Random effects meta-analysis will be conducted, if feasible and appropriate. Additional analyses will be performed to explore potential sources of heterogeneity. This systematic review and meta-analysis will provide a synthesis of studies evaluating the association of working conditions and systemic inflammation. We anticipate our findings to identify knowledge gaps in the literature that future research should address. Moreover, results of our review may provide implications for corporate and public policy action for employee health promotion and prevention of occupational stress. PROSPERO ID: CRD42020166887.
Sections du résumé
BACKGROUND
With the dynamic advancement of digitalization, working environments are changing and risk for employee stress may be increasing. Work stress has been associated with a dysregulation of inflammatory processes as a component of immune function. Systemic low-grade inflammation is discussed as a key player in the relation between stress exposure and chronic illness, such as cardiovascular diseases. The objective of this investigation will be to evaluate the association of working conditions including digital technology use and systemic inflammation among employees.
METHODS
We designed and registered a study protocol for a systematic review of randomized controlled trials and prospective non-randomized studies (e.g., cohort, interrupted time series, or before-after studies). We will include studies conducted among adult workers reporting associations of working conditions and inflammatory activity. The outcome will be biomarkers of systemic low-grade inflammation on cell, plasma molecule and intracellular level, such as C-reactive protein, or different types of leukocytes, cytokines, etc. Literature searches will be conducted in several electronic databases (from January 1982 onwards), including PubMed/MEDLINE, Embase, PsycINFO, Web of Science, and CENTRAL. Two reviewers will independently screen all retrieved records, full-text articles, and extract data. The study methodological quality (or bias) will be appraised using appropriate tools. Our results will be described qualitatively. Random effects meta-analysis will be conducted, if feasible and appropriate. Additional analyses will be performed to explore potential sources of heterogeneity.
DISCUSSION
This systematic review and meta-analysis will provide a synthesis of studies evaluating the association of working conditions and systemic inflammation. We anticipate our findings to identify knowledge gaps in the literature that future research should address. Moreover, results of our review may provide implications for corporate and public policy action for employee health promotion and prevention of occupational stress.
SYSTEMATIC REVIEW REGISTRATION
PROSPERO ID: CRD42020166887.
Identifiants
pubmed: 32988415
doi: 10.1186/s13643-020-01463-x
pii: 10.1186/s13643-020-01463-x
pmc: PMC7523305
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
221Références
Environ Int. 2019 Jul;128:11-12
pubmed: 31029974
J Appl Psychol. 2007 Mar;92(2):438-54
pubmed: 17371090
J Appl Psychol. 2001 Jun;86(3):499-512
pubmed: 11419809
Syst Rev. 2015 Jan 01;4:1
pubmed: 25554246
BMJ. 2019 Aug 28;366:l4898
pubmed: 31462531
Lancet. 2012 Oct 27;380(9852):1491-7
pubmed: 22981903
Scand J Work Environ Health. 2010 Mar;36(2):96-108
pubmed: 20087536
J Clin Epidemiol. 2000 Nov;53(11):1119-29
pubmed: 11106885
Am J Public Health. 1988 Oct;78(10):1336-42
pubmed: 3421392
Psychol Med. 2017 Jun;47(8):1342-1356
pubmed: 28122650
Control Clin Trials. 1986 Sep;7(3):177-88
pubmed: 3802833
Psychol Bull. 2004 Jul;130(4):601-30
pubmed: 15250815
J Clin Epidemiol. 2013 Jul;66(7):719-25
pubmed: 23312392
J Clin Epidemiol. 2011 Apr;64(4):401-6
pubmed: 21208779
Scand J Work Environ Health. 2020 Jan 1;46(1):19-31
pubmed: 31608963
BMJ. 2009 Jul 21;339:b2700
pubmed: 19622552
Science. 2010 Dec 17;330(6011):1621
pubmed: 21163993
Brain Behav Immun. 2015 Feb;44:253-69
pubmed: 25205395
BMJ. 2008 Apr 26;336(7650):924-6
pubmed: 18436948
Psychoneuroendocrinology. 2019 Jul;105:164-171
pubmed: 30826163
BMJ. 2015 Jan 02;350:g7647
pubmed: 25555855
Int Arch Occup Environ Health. 2015 Nov;88(8):997-1014
pubmed: 25687981
Curr Cardiol Rep. 2017 Sep 20;19(11):111
pubmed: 28932967
J Psychosom Res. 2016 Dec;91:1-8
pubmed: 27894456
J Appl Psychol. 2000 Feb;85(1):65-74
pubmed: 10740957
J Occup Health Psychol. 1996 Jan;1(1):27-41
pubmed: 9547031
Scand J Work Environ Health. 1989 Aug;15(4):271-9
pubmed: 2772582
Brain Behav Immun. 2017 Aug;64:208-219
pubmed: 28089638
Res Synth Methods. 2018 Mar;9(1):132-140
pubmed: 29106058
BMJ. 2017 Sep 21;358:j4008
pubmed: 28935701
Environ Int. 2016 Jul-Aug;92-93:611-6
pubmed: 26827182
Ann Occup Environ Med. 2019 May 28;31:e5
pubmed: 31543966
BMJ Open. 2018 Aug 29;8(8):e022612
pubmed: 30158233
Methods Mol Biol. 2012;934:39-75
pubmed: 22933140
BMJ. 2016 Oct 12;355:i4919
pubmed: 27733354
J Clin Epidemiol. 2018 Mar;95:7-18
pubmed: 29203419
BMJ. 1997 Sep 13;315(7109):629-34
pubmed: 9310563
Occup Environ Med. 2010 Feb;67(2):78-83
pubmed: 19773285
Health Technol Assess. 2003;7(41):1-90
pubmed: 14670218
Stroke. 2015 Feb;46(2):557-9
pubmed: 25563644
BMJ. 2004 Jun 19;328(7454):1490
pubmed: 15205295
Front Hum Neurosci. 2017 Jun 20;11:316
pubmed: 28676747
Am J Epidemiol. 2005 Feb 1;161(3):280-8
pubmed: 15671260
BMJ. 2009 Jul 21;339:b2535
pubmed: 19622551
Brain Behav Immun. 2010 Nov;24(8):1332-9
pubmed: 20599495
Syst Rev. 2016 Dec 5;5(1):210
pubmed: 27919275
Pers J. 1982 Oct;61(10):753-7
pubmed: 10258012
Int J Technol Assess Health Care. 2012 Apr;28(2):138-44
pubmed: 22559755
Neurosci Biobehav Rev. 2010 Sep;35(1):115-21
pubmed: 20026349
Int J Epidemiol. 2002 Feb;31(1):115-23
pubmed: 11914306
Curr Cardiol Rep. 2015 Sep;17(9):630
pubmed: 26238744
BMJ. 2008 May 3;336(7651):995-8
pubmed: 18456631
Psychosom Med. 1993 Jul-Aug;55(4):364-79
pubmed: 8416086
BMJ. 2011 Jul 22;343:d4002
pubmed: 21784880
BMJ. 2003 Sep 6;327(7414):557-60
pubmed: 12958120