Genome-wide association study identifies 48 common genetic variants associated with handedness.

Adult Aged Female Functional Laterality / genetics Gene Frequency / genetics Genetic Loci / genetics Genetic Variation / genetics Genome-Wide Association Study Humans Linkage Disequilibrium Male Middle Aged Polymorphism, Single Nucleotide / genetics Quantitative Trait, Heritable Sex Factors

Journal

Nature human behaviour
ISSN: 2397-3374
Titre abrégé: Nat Hum Behav
Pays: England
ID NLM: 101697750

Informations de publication

Date de publication:
01 2021
Historique:
received: 03 02 2020
accepted: 18 08 2020
pubmed: 30 9 2020
medline: 5 3 2021
entrez: 29 9 2020
Statut: ppublish

Résumé

Handedness has been extensively studied because of its relationship with language and the over-representation of left-handers in some neurodevelopmental disorders. Using data from the UK Biobank, 23andMe and the International Handedness Consortium, we conducted a genome-wide association meta-analysis of handedness (N = 1,766,671). We found 41 loci associated (P < 5 × 10

Identifiants

DOI: 10.1038/s41562-020-00956-y PMID: 32989287 PMC: PMC7116623
pubmed: 32989287
doi: 10.1038/s41562-020-00956-y
pii: 10.1038/s41562-020-00956-y
pmc: PMC7116623
mid: EMS109952
doi:

Types de publication

Journal Article Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

59-70

Subventions

Organisme : Medical Research Council
ID : MC_UU_00006/1
Pays : United Kingdom
Organisme : Wellcome Trust (Wellcome)
ID : 090532, 106130, 098381, 203141, 212259, 095101, 200837, 099673/Z/12/Z
Organisme : Medical Research Council
ID : MC_UU_00011/1
Pays : United Kingdom
Organisme : Department of Health | National Health and Medical Research Council (NHMRC)
ID : APP1103623
Organisme : Medical Research Council
ID : MC_PC_15018
Pays : United Kingdom
Organisme : NIMH NIH HHS
ID : R01 MH058799
Pays : United States
Organisme : DH | NIHR | Health Services Research Programme (NIHR Health Services Research Programme)
ID : 5P50HD028138-27
Organisme : Department of Education and Training | Australian Research Council (ARC)
ID : DE180100976
Organisme : Medical Research Council
ID : MC_UU_00007/10
Pays : United Kingdom
Organisme : NIDDK NIH HHS
ID : R01 DK092127
Pays : United States
Organisme : British Heart Foundation
ID : RG/18/13/33946
Pays : United Kingdom
Organisme : British Heart Foundation
ID : CH/12/2/29428
Pays : United Kingdom
Organisme : NIMH NIH HHS
ID : RC2 MH089951
Pays : United States
Organisme : DH | NIHR | Health Services Research Programme (NIHR Health Services Research Programme)
ID : NF-SI-0617-10090
Organisme : NICHD NIH HHS
ID : P50 HD028138
Pays : United States
Organisme : NIMH NIH HHS
ID : RC2 MH089995
Pays : United States
Organisme : British Heart Foundation
ID : RG/13/13/30194
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 086596
Pays : United Kingdom
Organisme : Department of Health | National Health and Medical Research Council (NHMRC)
ID : APP1104818
Organisme : Medical Research Council
ID : MC_UU_12015/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_12013/4
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : U01 CA182913
Pays : United States
Organisme : Department of Health | National Health and Medical Research Council (NHMRC)
ID : APP1137714

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Auteurs

Gabriel Cuellar-Partida (G)

The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia.
23andMe, Inc., Sunnyvale, CA, USA.
ORCID: 0000-0001-7648-4097

Joyce Y Tung (JY)

23andMe, Inc., Sunnyvale, CA, USA.

Nicholas Eriksson (N)

23andMe, Inc., Sunnyvale, CA, USA.

Eva Albrecht (E)

Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.

Fazil Aliev (F)

Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA.
Karabuk University, Faculty of Business, Karabük, Turkey.
ORCID: 0000-0001-8357-4699

Ole A Andreassen (OA)

NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
ORCID: 0000-0002-4461-3568

Inês Barroso (I)

Human Genetics, Wellcome Sanger Institute, Hinxton, UK.
MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
ORCID: 0000-0001-5800-4520

Jacques S Beckmann (JS)

Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.
ORCID: 0000-0002-9741-1900

Marco P Boks (MP)

Department of Psychiatry, UMC Utrecht Brain Center, University Utrecht, Utrecht, The Netherlands.
ORCID: 0000-0001-6163-7484

Dorret I Boomsma (DI)

Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.
Amsterdam Public Health research institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
ORCID: 0000-0002-7099-7972

Heather A Boyd (HA)

Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
ORCID: 0000-0001-6849-9985

Monique M B Breteler (MMB)

Population Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
ORCID: 0000-0002-0626-9305

Harry Campbell (H)

Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.

Daniel I Chasman (DI)

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.
ORCID: 0000-0003-3357-0862

Lynn F Cherkas (LF)

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.

Gail Davies (G)

Department of Psychology, University of Edinburgh, Edinburgh, UK.
Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

Eco J C de Geus (EJC)

Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.
Amsterdam Public Health research institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
ORCID: 0000-0001-6022-2666

Ian J Deary (IJ)

Department of Psychology, University of Edinburgh, Edinburgh, UK.
Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0002-1733-263X

Panos Deloukas (P)

William Harvey Research Institute, Barts and the London Medical School, and the Centre for Genomic Health, Queen Mary University of London, London, UK.
ORCID: 0000-0001-9251-070X

Danielle M Dick (DM)

Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA.
Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA.
ORCID: 0000-0002-1636-893X

David L Duffy (DL)

Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

Johan G Eriksson (JG)

Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Folkhälsan Research Center, Helsinki, Finland.
Singapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore, Singapore.
Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Tõnu Esko (T)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Bjarke Feenstra (B)

Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
ORCID: 0000-0003-1478-649X

Frank Geller (F)

Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
ORCID: 0000-0002-9238-3269

Christian Gieger (C)

Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, Neuherberg, Germany.

Ina Giegling (I)

University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.

Scott D Gordon (SD)

Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
ORCID: 0000-0001-7623-328X

Jiali Han (J)

Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN, USA.
Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA.

Thomas F Hansen (TF)

Institute of Biological Psychiatry, Mental Health Services of Copenhagen, Copenhagen, Denmark.
Danish Headache Center, Copenhagen University Hospital, Glostrup, Denmark.
ORCID: 0000-0001-6703-7762

Annette M Hartmann (AM)

University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.

Caroline Hayward (C)

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0002-9405-9550

Kauko Heikkilä (K)

Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.

Andrew A Hicks (AA)

Institute for Biomedicine, Eurac Research, Bolzano, Italy.
ORCID: 0000-0001-6320-0411

Joel N Hirschhorn (JN)

Division of Endocrinology, Boston Children's Hospital, Boston, MA, USA.
Department of Genetics, Harvard Medical School, Boston, MA, USA.
Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
ORCID: 0000-0002-1650-7901

Jouke-Jan Hottenga (JJ)

Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.
Amsterdam Public Health research institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
ORCID: 0000-0002-5668-2368

Jennifer E Huffman (JE)

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0002-9672-2491

Liang-Dar Hwang (LD)

The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia.
ORCID: 0000-0002-5535-2199

M Arfan Ikram (MA)

Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
ORCID: 0000-0003-0372-8585

Jaakko Kaprio (J)

Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.
Department of Public Health, University of Helsinki, Helsinki, Finland.
ORCID: 0000-0002-3716-2455

John P Kemp (JP)

The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia.
Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
ORCID: 0000-0002-9105-2249

Kay-Tee Khaw (KT)

Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Norman Klopp (N)

Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.

Bettina Konte (B)

University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
ORCID: 0000-0001-5287-308X

Zoltan Kutalik (Z)

Center for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland.
Swiss Institute of Bioinformatics, Lausanne, Switzerland.
ORCID: 0000-0001-8285-7523

Jari Lahti (J)

Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.
Turku Institute for Advanced Studies, University of Turku, Turku, Finland.
Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
ORCID: 0000-0002-4310-5297

Xin Li (X)

Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN, USA.
Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA.
ORCID: 0000-0002-0135-8800

Ruth J F Loos (RJF)

MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
ORCID: 0000-0002-8532-5087

Michelle Luciano (M)

Department of Psychology, University of Edinburgh, Edinburgh, UK.
Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0002-7306-3008

Sigurdur H Magnusson (SH)

deCODE Genetics, Reykjavik, Iceland.
ORCID: 0000-0001-6669-3071

Massimo Mangino (M)

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
ORCID: 0000-0002-2167-7470

Pedro Marques-Vidal (P)

Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
ORCID: 0000-0002-4548-8500

Nicholas G Martin (NG)

Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
ORCID: 0000-0003-4069-8020

Wendy L McArdle (WL)

Bristol Medical School, University of Bristol, Bristol, UK.
ORCID: 0000-0002-0605-5403

Mark I McCarthy (MI)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK.
Human Genetics, Genentech, South San Francisco, CA, USA.
ORCID: 0000-0002-4393-0510

Carolina Medina-Gomez (C)

Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
ORCID: 0000-0001-7999-5538

Mads Melbye (M)

Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
ORCID: 0000-0001-8264-6785

Scott A Melville (SA)

Institute for Biomedicine, Eurac Research, Bolzano, Italy.

Andres Metspalu (A)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
ORCID: 0000-0002-3718-796X

Lili Milani (L)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
ORCID: 0000-0002-5323-3102

Vincent Mooser (V)

Service of Clinical Chemistry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Mari Nelis (M)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
ORCID: 0000-0001-9748-1020

Dale R Nyholt (DR)

Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
ORCID: 0000-0001-7159-3040

Kevin S O'Connell (KS)

NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
ORCID: 0000-0002-6865-8795

Roel A Ophoff (RA)

Department of Human Genetics, University California Los Angeles, Los Angeles, CA, USA.
Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University California Los Angeles, Los Angeles, CA, USA.
Department of Psychiatry, Erasmus University Medical Center, Rotterdam, The Netherlands.
ORCID: 0000-0002-8287-6457

Cameron Palmer (C)

Department of Computer Science, Columbia University, New York, NY, USA.

Aarno Palotie (A)

Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.

Teemu Palviainen (T)

Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.
ORCID: 0000-0002-7847-8384

Guillaume Pare (G)

Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
ORCID: 0000-0002-6795-4760

Lavinia Paternoster (L)

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
ORCID: 0000-0003-2514-0889

Leena Peltonen (L)

Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.

Brenda W J H Penninx (BWJH)

Amsterdam Public Health research institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Department of Psychiatry, Amsterdam UMC, VU University, Amsterdam, The Netherlands.

Ozren Polasek (O)

Department of Public Health, University of Split School of Medicine, Split, Croatia.
Research Unit, Psychiatric Hospital Sveti Ivan, Zagreb, Croatia.
ORCID: 0000-0002-5765-1862

Peter P Pramstaller (PP)

Institute for Biomedicine, Eurac Research, Bolzano, Italy.

Inga Prokopenko (I)

Section of Statistical Multi-Omics, Department of Clinical and Experimental Medicine, University of Surrey, Guildford, UK.
Section of Genomics of Common Disease, Department of Medicine, Imperial College London, London, UK.
ORCID: 0000-0003-1624-7457

Katri Raikkonen (K)

Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.

Samuli Ripatti (S)

Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.
ORCID: 0000-0002-0504-1202

Fernando Rivadeneira (F)

Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
ORCID: 0000-0001-9435-9441

Igor Rudan (I)

Centre for Global Health Research, The Usher Institute, University of Edinburgh, Edinburgh, UK.
ORCID: 0000-0001-6993-6884

Dan Rujescu (D)

University Clinic and Outpatient Clinic for Psychiatry, Psychotherapy and Psychosomatics, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.

Johannes H Smit (JH)

Amsterdam Public Health research institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Department of Psychiatry, Amsterdam UMC, VU University, Amsterdam, The Netherlands.
ORCID: 0000-0002-2062-8378

George Davey Smith (GD)

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
ORCID: 0000-0002-1407-8314

Jordan W Smoller (JW)

Department of Psychiatry and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.
ORCID: 0000-0002-0381-6334

Nicole Soranzo (N)

Human Genetics, Wellcome Sanger Institute, Hinxton, UK.

Tim D Spector (TD)

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
ORCID: 0000-0002-9795-0365

Beate St Pourcain (BS)

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Max Planck Institute for Psycholinguistics, Wundtlaan, Nijmegen, The Netherlands.
Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
ORCID: 0000-0002-4680-3517

John M Starr (JM)

Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
Centre for Cognitive Ageing and Cognitive Epidemilogy, University of Edinburgh, Edinburgh, UK.

Hreinn Stefánsson (H)

deCODE Genetics, Reykjavik, Iceland.
ORCID: 0000-0002-9331-6666

Stacy Steinberg (S)

deCODE Genetics, Reykjavik, Iceland.
ORCID: 0000-0001-7726-5152

Maris Teder-Laving (M)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
ORCID: 0000-0002-5872-1850

Gudmar Thorleifsson (G)

deCODE Genetics, Reykjavik, Iceland.

Kári Stefánsson (K)

deCODE Genetics, Reykjavik, Iceland.
ORCID: 0000-0003-1676-864X

Nicholas J Timpson (NJ)

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
ORCID: 0000-0002-7141-9189

André G Uitterlinden (AG)

Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
ORCID: 0000-0002-7276-3387

Cornelia M van Duijn (CM)

Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

Frank J A van Rooij (FJA)

Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
ORCID: 0000-0002-8600-9852

Jaqueline M Vink (JM)

Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.
Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands.
ORCID: 0000-0003-3910-3528

Peter Vollenweider (P)

Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Eero Vuoksimaa (E)

Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.

Gérard Waeber (G)

Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
ORCID: 0000-0003-4193-788X

Nicholas J Wareham (NJ)

MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.

Nicole Warrington (N)

The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia.
ORCID: 0000-0003-4195-775X

Dawn Waterworth (D)

Human Genetics, GlaxoSmithKline, Collegeville, PA, USA.

Thomas Werge (T)

Institute of Biological Psychiatry, Mental Health Services of Copenhagen, Copenhagen, Denmark.
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation's IPSYCH Initiative, Copenhagen, Denmark.
ORCID: 0000-0003-1829-0766

H-Erich Wichmann (HE)

Institute of Epidemiology, Helmholtz Center, Munich, Germany.

Elisabeth Widen (E)

Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.

Gonneke Willemsen (G)

Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands.

Alan F Wright (AF)

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

Margaret J Wright (MJ)

Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
Centre for Advanced Imaging, The University of Queensland, Brisbane, Queensland, Australia.
ORCID: 0000-0001-7133-4970

Mousheng Xu (M)

Department of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard Medical School, Boston, MA, USA.

Jing Hua Zhao (JH)

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
ORCID: 0000-0002-1463-5870

Peter Kraft (P)

Department of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard Medical School, Boston, MA, USA.
ORCID: 0000-0002-4472-8103

David A Hinds (DA)

23andMe, Inc., Sunnyvale, CA, USA.
ORCID: 0000-0002-4911-803X

Cecilia M Lindgren (CM)

Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.
ORCID: 0000-0002-4903-9374

Reedik Mägi (R)

Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.

Benjamin M Neale (BM)

Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Analytic and Translational Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
ORCID: 0000-0003-1513-6077

David M Evans (DM)

The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia. d.evans1@uq.edu.au.
MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. d.evans1@uq.edu.au.
ORCID: 0000-0003-0663-4621

Sarah E Medland (SE)

The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia. Sarah.Medland@qimrberghofer.edu.au.
Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. Sarah.Medland@qimrberghofer.edu.au.
ORCID: 0000-0003-1382-380X

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Genome-wide association study identifies 48...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Genome-wide association study identifies 48...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Dominance cérébrale › Latéralité fonctionnelle › Genome-wide association study identifies 48...
questionsmedicales.fr › Phénomènes génétiques › Fréquence d'allèle › Genome-wide association study identifies 48...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Locus génétiques › Genome-wide association study identifies 48...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Genome-wide association study identifies 48...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Épidémiologie moléculaire › Étude d'association pangénomique › Genome-wide association study identifies 48...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Genome-wide association study identifies 48...
questionsmedicales.fr › Phénomènes génétiques › Liaison génétique › Déséquilibre de liaison › Genome-wide association study identifies 48...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Genome-wide association study identifies 48...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Polymorphisme génétique › Polymorphisme de nucléotide simple › Genome-wide association study identifies 48...
questionsmedicales.fr › Phénomènes génétiques › Modes de transmission héréditaire › Caractère quantitatif héréditaire › Genome-wide association study identifies 48...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Facteurs épidémiologiques › Facteurs sexuels › Genome-wide association study identifies 48...