Corpora amylacea in sputum smears: Incidence and clinical significance.


Journal

Cytopathology : official journal of the British Society for Clinical Cytology
ISSN: 1365-2303
Titre abrégé: Cytopathology
Pays: England
ID NLM: 9010345

Informations de publication

Date de publication:
01 2021
Historique:
received: 31 07 2020
revised: 19 08 2020
accepted: 18 09 2020
pubmed: 30 9 2020
medline: 14 10 2021
entrez: 29 9 2020
Statut: ppublish

Résumé

To examine conventional sputum smears for the presence of corpora amylacea (CA), determining their incidence and clinical significance. A retrospective 4-year cohort study was undertaken of sputum samples from 1176 consecutive patients for the presence of CA. Variables such as age, sex, smoking status, and the presence or absence of haemoptysis were extracted from the medical record. A random group of 50 patients was selected as a control group, and a random group of 50 patients whose ages were below 49 years was also included as an age-based control. A total of 1075 of the initial cohort of consecutive patients were included in the study. from these, there were 6898 sputum smears, of which 1.91% (132 smears) contained CA, corresponding to 9.86% of the cohort of patients (106 patients). There was a strong, positive, statistically significant correlation between age and CA presence (τ The presence of CA in sputum smears is related to age, being much more frequent in older people. Moreover, CA are related to non-neoplastic lung diseases.

Identifiants

pubmed: 32989812
doi: 10.1111/cyt.12919
doi:

Substances chimiques

Starch 9005-25-8

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108-114

Informations de copyright

© 2020 John Wiley & Sons Ltd.

Références

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Auteurs

Rafael Martínez-Girón (R)

INCLÍNICA Foundation for Clinical, Pneumological and Carcinogenic Research, Oviedo, Spain.

Liron Pantanowitz (L)

Department of Pathology & Clinical Labs, University of Michigan, Ann Arbor, MI, USA.

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Classifications MeSH